方案
99%
mp
>240 °C (dec.) (lit.)
SMILES字符串
NC(Cc1ccc(Cl)cc1)C(O)=O
InChI
1S/C9H10ClNO2/c10-7-3-1-6(2-4-7)5-8(11)9(12)13/h1-4,8H,5,11H2,(H,12,13)
InChI key
NIGWMJHCCYYCSF-UHFFFAOYSA-N
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生化/生理作用
色氨酸羟化酶抑制剂。
警示用语：
Danger
危险声明
预防措施声明
危险分类
Acute Tox. 3 Oral - Skin Sens. 1
储存分类代码
6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
法规信息
新产品
此项目有
Silvina L Diaz et al.
The European journal of neuroscience, 38(5), 2650-2658 (2013-07-12)
Increased adult neurogenesis is a major neurobiological correlate of the beneficial effects of antidepressants. Indeed, selective serotonin (5-HT) re-uptake inhibitors, which increase 5-HT transmission, enhance adult neurogenesis in the dentate gyrus (DG) of the hippocampus. However, the consequences of 5-HT
Matilda Bäckberg et al.
Clinical toxicology (Philadelphia, Pa.), 53(9), 856-864 (2015-08-22)
3-Methoxy-phencyclidine (3-MeO-PCP) and 4-methoxy-phencyclidine (4-MeO-PCP) are analogs of and drug substitutes for the dissociative substance PCP ("Angel dust"), a recreational drug that was most popular in the 1970s. In Sweden, use of methoxylated PCP analogs was noted starting in mid-2013
E Manová et al.
The British journal of dermatology, 171(6), 1368-1374 (2014-08-27)
Octocrylene (OCT) is an ultraviolet (UV) filter used in personal care products (PCPs) to prevent sun-related skin damage. OCT is photostable and has the ability to photostabilize other UV filters, which has recently led to its increased use in PCPs.
Mark J Airhart et al.
Neurotoxicology and teratology, 34(1), 152-160 (2011-09-07)
In this study, p-chlorophenylalanine (pCPA), an inhibitor of tryptophan hydroxylase (the rate limiting enzyme of serotonin synthesis), was used to reduce serotonin (5HT) levels during early development in zebrafish embryos. One day old dechorionated embryos were treated with 25 μM
Alicia Izquierdo et al.
Behavioural brain research, 233(2), 494-499 (2012-06-02)
Aside from the well-known influence of serotonin (5-hydroxytryptamine, 5-HT) on emotional regulation, more recent investigations have revealed the importance of this monoamine in modulating cognition. Parachlorophenylalanine (PCPA) depletes 5-HT by inhibiting tryptophan hydroxylase, the enzyme required for 5-HT synthesis and
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