vapor density
4.46 (vs air)
assay
97%
mp
196-198 °C (lit.)
SMILES string
Cl.Nc1ccccc1
InChI
1S/C6H7N.ClH/c7-6-4-2-1-3-5-6;/h1-5H,7H2;1H
InChI key
MMCPOSDMTGQNKG-UHFFFAOYSA-N
Application
Aniline hydrochloride was used in the preparation of polyaniline coated poly(styrene-co-styrene sulfonate) nanoparticles. It was used to study the induction of Nei-like DNA glycosylases (NEIL1/2)-mediated base excision repair(BER) in rat spleen and 8-oxoguanine glycosylase 1-mediated BER due to aniline exposure.
Biochem/physiol Actions
苯胺的急性毒性与其体内活化生成4-羟基苯胺并与血红蛋白形成加合物有关。在红细胞中，这与铁的释放和高铁血红蛋白的积累以及溶血性贫血和脾脏炎症的发展有关。长期给药经常在脾脏中观察到肿瘤形成。
Other Notes
This product has been replaced by A8524-ALDRICH | Aniline hydrochloride ≥99%
signalword
Danger
Hazard Classifications
Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Carc. 2 - Eye Dam. 1 - Muta. 2 - Skin Sens. 1 - STOT RE 1
存储类别
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 3
flash_point_f
381.2 °F - closed cup
flash_point_c
194 °C - closed cup
ppe
Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges
法规信息
新产品
此项目有
Preparation of PANI-coated poly (styrene-co-styrene sulfonate) nanoparticles.
Kim BJ, et al.
Polymer, 43(1), 111-116 (2002)
Huaxian Ma et al.
Toxicology and applied pharmacology, 251(1), 1-7 (2010-12-15)
The mechanisms by which aniline exposure elicits splenotoxic response, especially the tumorigenic response, are not well-understood. Earlier, we have shown that aniline-induced oxidative stress is associated with increased oxidative DNA damage in rat spleen. The base excision repair (BER) pathway
Conghui Tang et al.
Journal of the American Chemical Society, 134(46), 18924-18927 (2012-11-08)
A novel and efficient copper-catalyzed azidation reaction of anilines via C-H activation has been developed. This method, in which the primary amine acts as a directing group by coordinating to the metal center, provides ortho azidation products regioselectively under mild
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| E1641-2MG | 04061833602034 |
| E1641-10MG | 04061833602027 |