assay
98%
form
solid
mp
92-95 °C (lit.)
functional group
ester, nitro
SMILES string
CC(C)(C)C(=O)Oc1ccc(cc1)[N+]([O-])=O
InChI
1S/C11H13NO4/c1-11(2,3)10(13)16-9-6-4-8(5-7-9)12(14)15/h4-7H,1-3H3
InChI key
QADVJDGFQGNSIF-UHFFFAOYSA-N
General description
4-Nitrophenyl trimethylacetate undergoes hydrolysis catalysed by cytoplasmic aldehyde dehydrogenase in presence of NAD+, NADH, propionaldehyde, chloral hydrate, diethylstilboestrol and p-nitrobenzaldehyde (modifiers).
Application
4-Nitrophenyl trimethylacetate was used as sensitive probe to study the catalytic activity of carboxypeptidase Y.
The trimethylacetyl-transglutaminase complex.
J E Folk
Methods in enzymology, 87, 36-42 (1982-01-01)
T M Kitson
The Biochemical journal, 257(2), 573-578 (1989-01-15)
The effects of modifiers (NAD+, NADH, propionaldehyde, chloral hydrate, diethylstilboestrol and p-nitrobenzaldehyde) on the hydrolysis of p-nitrophenyl (PNP) pivalate (PNP trimethylacetate) catalysed by cytoplasmic aldehyde dehydrogenase are reported. In each case a different inhibition pattern is obtained to that observed
Studies of the esterase activity of cytosolic aldehyde dehydrogenase using sterically hindered and cyclic substrates.
K E Kitson et al.
Advances in experimental medicine and biology, 372, 45-52 (1995-01-01)
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| 135046-25G | 04061831818536 |