137111
乙氧基乙酸
98%
别名:
O-乙基羟基乙酸
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关于此项目
线性分子式:
C2H5OCH2COOH
化学文摘社编号:
分子量:
104.10
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
210-978-2
Beilstein/REAXYS Number:
1743037
MDL number:
Assay:
98%
assay
98%
refractive index
n20/D 1.419 (lit.)
bp
97-100 °C/11 mmHg (lit.)
density
1.102 g/mL at 25 °C (lit.)
functional group
carboxylic acid, ether
SMILES string
CCOCC(O)=O
InChI
1S/C4H8O3/c1-2-7-3-4(5)6/h2-3H2,1H3,(H,5,6)
InChI key
YZGQDNOIGFBYKF-UHFFFAOYSA-N
General description
Ethoxyacetic acid is biomarker of exposure to widely used industrial chemicals such as alkyl-substituted ethylene glycols and other aliphatic ethers.
Application
Ethoxyacetic acid is metabolite of glycol ether alkoxy acid and was used to evaluate its toxicity in embryonic stem cell test in mouse. It was used in zebrafish embryotoxicity test to study chemical toxicity after exposure of the complete vertebrate embryo during embryogenesis in ovo.
Biochem/physiol Actions
Ethoxyacetic acid induces testicular toxicity in rats in vivo .
signalword
Danger
hcodes
Hazard Classifications
Eye Dam. 1 - Skin Corr. 1B
存储类别
8A - Combustible corrosive hazardous materials
wgk
WGK 3
flash_point_f
206.6 °F - closed cup
flash_point_c
97 °C - closed cup
ppe
Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter
法规信息
新产品
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J C Hoflack et al.
Mutation research, 341(4), 281-287 (1995-02-01)
Ethylene glycol ethers, their aldehyde and their acid metabolites were evaluated for their mutagenicity with the Ames test. The Salmonella typhimurium his- tester strains TA 97a, TA 98, TA 100 and TA 102 were used with and without rat S9
D Groeseneken et al.
International archives of occupational and environmental health, 61(4), 249-254 (1989-01-01)
A sensitive and specific method for the determination in urine of alkoxyacetic acids, the metabolites of ethylene glycol monoalkyl ethers, was developed by combining the advantages of two previously described methods. The acids were determined gas chromatographically as their pentafluorobenzylesters.
T Sakai et al.
International archives of occupational and environmental health, 64(7), 495-498 (1993-01-01)
In control subjects and workers exposed to glycol ethers and their acetates, we determined the urinary metabolites (three alkoxyacetic acids) by a simple and rapid method. Levels of urinary metabolites were significantly higher in the solvent workers than in the
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| 137111-25G | 04061836673956 |
| 137111-100G | 04061836682309 |