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Merck
CN

138061

N-乙酰基-L-半胱氨酸

98%

别名:

LNAC, NAC

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关于此项目

线性分子式:
HSCH2CH(NHCOCH3)CO2H
化学文摘社编号:
分子量:
163.19
Beilstein:
1724426
EC 号:
MDL编号:
UNSPSC代码:
12352209
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方案

98%

旋光性

[α]25/D +4.5°, c = 2 in H2O

mp

106-108 °C (lit.)

SMILES字符串

CC(=O)N[C@@H](CS)C(O)=O

InChI

1S/C5H9NO3S/c1-3(7)6-4(2-10)5(8)9/h4,10H,2H2,1H3,(H,6,7)(H,8,9)/t4-/m0/s1

InChI key

PWKSKIMOESPYIA-BYPYZUCNSA-N

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应用

Useful reagent in a variety of biochemical applications, such as the derivatization of anticancer triazenes and the synthesis of matlystatin A via 1,4-Michael addition.

生化/生理作用

抗氧化剂和黏液溶解剂(mucolytic agent)。增加细胞池的自由基清除剂。 据报道可防止神经细胞凋亡,但会诱导平滑肌细胞凋亡。抑制HIV复制。可作为微粒体谷胱甘肽转移酶的底物。

象形图

Exclamation mark

警示用语:

Warning

危险声明

危险分类

Eye Irrit. 2

储存分类代码

13 - Non Combustible Solids

WGK

WGK 2

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)

法规信息

新产品
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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Journal of the Chemical Society. Perkin Transactions 1, 3241-3241 (1991)
Tetrahedron Letters, 34, 8477-8477 (1993)
Marialucia Gallorini et al.
Biomaterials, 56, 114-128 (2015-05-03)
Oxidative stress due to increased formation of reactive oxygen species (ROS) in target cells of dental resin monomers like 2-hydroxyethyl methacrylate (HEMA) is a major mechanism underlying the disturbance of vital cell functions including mineralization and differentiation, responses of the
Kristell Le Gal et al.
Science translational medicine, 7(308), 308re8-308re8 (2015-10-09)
Antioxidants in the diet and supplements are widely used to protect against cancer, but clinical trials with antioxidants do not support this concept. Some trials show that antioxidants actually increase cancer risk and a study in mice showed that antioxidants
Francielli Licks et al.
World journal of gastroenterology, 21(43), 12351-12360 (2015-11-26)
To evaluate the antioxidant effect of N-acetylcysteine (NAC) on the stomach of rats with portal hypertension. Twenty-four male Wistar rats weighing ± 250 g were divided into four experimental groups (n = 6 each): Sham-operated (SO), SO + NAC, partial

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