Quality Level
assay
96%
form
powder
mp
181-183 °C (lit.)
solubility
alcohol: very slightly soluble, diethyl ether: very slightly soluble, hydrochloric acid: freely soluble (hot)
functional group
nitro
SMILES string
Oc1ccc([N+]([O-])=O)c2cccnc12
InChI
1S/C9H6N2O3/c12-8-4-3-7(11(13)14)6-2-1-5-10-9(6)8/h1-5,12H
InChI key
RJIWZDNTCBHXAL-UHFFFAOYSA-N
Application
8-羟基-5-硝基喹啉用于合成新型CO2可溶性8-羟基喹啉螯合剂。
Biochem/physiol Actions
8-羟基-5-硝基喹啉是一种有效的抗菌剂和抗癌剂。这是治疗革兰氏阴性杆菌所致各种尿路感染的有效药物。
signalword
Danger
Hazard Classifications
Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
C Pelletier et al.
Antimicrobial agents and chemotherapy, 39(3), 707-713 (1995-03-01)
The antibacterial activity of nitroxoline (NIT), an antibiotic used in the treatment of acute or recurrent urinary tract infections caused by Escherichia coli, is decreased in the presence of Mg2+ and Mn2+ but not Ca2+. In order to elucidate the
A V Yatsenko et al.
Acta crystallographica. Section C, Crystal structure communications, 58(Pt 1), o19-o21 (2002-01-10)
The crystal structures of 8-hydroxy-5-nitroquinoline, C9H6N2O3, (I), and 8-hydroxy-5-nitroquinolinium chloride, C9H7N2O3+*Cl-, (II), have been determined from X-ray powder data. In (I), the molecules are linked via moderately strong hydrogen bonds to form dimers. Such a packing motif is likely to
Mohamed M Ghoneim et al.
Bioelectrochemistry (Amsterdam, Netherlands), 80(2), 162-168 (2010-09-14)
Nitroxoline has been reduced at the mercury electrode in buffered solutions (pH 2-11) in two irreversible cathodic steps. The first step was attributed to reduction of -NO(2) group to the hydroxylamine stage and the second one to reduction-saturation of the
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| 货号 | GTIN |
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