141674
1-丙基哌嗪 二氢溴酸
96%
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关于此项目
经验公式（希尔记法）:
C7H16N2 · 2HBr
化学文摘社编号:
分子量:
290.04
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352100
EC Number:
264-759-1
MDL number:
Assay:
96%
InChI key
YTPQLWVHCBATKO-UHFFFAOYSA-N
InChI
1S/C7H16N2.2BrH/c1-2-5-9-6-3-8-4-7-9;;/h8H,2-7H2,1H3;2*1H
SMILES string
Br.Br.CCCN1CCNCC1
assay
96%
mp
259.5-264.5 °C (lit.)
solubility
water: soluble 50 mg/mL, clear, colorless
Quality Level
General description
1-n-Propylpiperazine dihydrobromide reacts with potassium thiocyanate to yield 1-(4-n-propyl)piperazine thioamide.
Application
1-n-Propylpiperazine dihydrobromide was used in the synthesis of amidines and sulfonamides of 5-and 6-amino-2,3-bis(4-alkyl-1-piperazazinyl)quinoxalines.
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
Anna Frymarkiewicz et al.
European journal of medicinal chemistry, 44(4), 1674-1681 (2008-11-08)
A series of 1-[[2-thiazol-5-yl-(2-aminoethyl)]-4-n-propyl]piperazine derivatives have been prepared and in vitro tested as H(3)-receptor antagonists (the electrically evoked contraction of the guinea pig jejunum). It appeared that by comparison of homologous pairs the 1-[[2-thiazol-5-yl-(2-methyl-2-phenylalkylaminoethyl)]-4-n-propyl]piperazine derivatives (4c1-4c3) have slightly higher activity
P F Fabio et al.
Journal of medicinal chemistry, 23(2), 201-206 (1980-02-01)
A series of amidines and sulfonamides of 5- and 6-amino-2,3-bis(4-alkyl-1-piperazinyl)quinoxalines was synthesized and tested against cecal and hepatic forms of Entamoeba histolytica infections in rats and hamsters, respectively. Four compounds (5, 6, 8, and 9) were found to have acceptable
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