方案
98%
mp
113-117 °C (lit.)
官能团
amine
phenyl
SMILES字符串
NC(=S)c1ccccc1
InChI
1S/C7H7NS/c8-7(9)6-4-2-1-3-5-6/h1-5H,(H2,8,9)
InChI key
QIOZLISABUUKJY-UHFFFAOYSA-N
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应用
硫代苯甲酰胺用于制备酰胺和脒加合物。它也用于合成 4-氧代-4H-亚甲基-3-碳硫代甲酸 N-苯酰胺。
警示用语：
Danger
危险声明
危险分类
Acute Tox. 3 Oral
储存分类代码
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
Chemical Research in Toxicology. In this issue.
Chemical research in toxicology, 21(7), 1320-1321 (2008-07-22)
A Kubo et al.
Archives of biochemistry and biophysics, 345(2), 271-277 (1997-10-06)
The flavin-containing monooxygenases (FMOs) are a family of flavoenzymes and contain one molecule of FAD per monomer. In order to demonstrate where FMO interacts with FAD, four mutants for the rat liver FMO1 protein were expressed in yeast and characterized.
Keisuke Ikehata et al.
Chemical research in toxicology, 21(7), 1432-1442 (2008-06-13)
Thiobenzamide (TB) is a potent hepatotoxin in rats, causing dose-dependent hyperbilirubinemia, steatosis, and centrolobular necrosis. These effects arise subsequent to and appear to result from the covalent binding of the iminosulfinic acid metabolite of TB to cellular proteins and phosphatidylethanolamine
P Joseph et al.
Placenta, 14(3), 309-319 (1993-05-01)
Human term placental peroxidase [donor: hydrogen peroxide (H2O2) oxidoreductase] from non-smoking women was purified by extraction of the membrane fraction with 0.5 M Ca2+ followed by affinity chromatography on concanavalin A, hydrophobic chromatography on phenyl sepharose CL-4B and gel filtration
Yakov M Koen et al.
Chemical research in toxicology, 26(4), 564-574 (2013-03-08)
Thioacetamide (TA) has long been known as a hepatotoxicant whose bioactivation requires S-oxidation to thioacetamide S-oxide (TASO) and then to the very reactive S,S-dioxide (TASO2). The latter can tautomerize to form acylating species capable of covalently modifying cellular nucleophiles including
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