151610
DL-3,4-二羟基杏仁酸
95%
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关于此项目
线性分子式:
(HO)2C6H3CH(OH)CO2H
化学文摘社编号:
分子量:
184.15
EC 号:
MDL编号:
UNSPSC代码:
12352100
PubChem化学物质编号:
NACRES:
NA.22
质量水平
方案
95%
mp
136-137 °C (dec.) (lit.)
官能团
carboxylic acid
hydroxyl
SMILES字符串
OC(C(O)=O)c1ccc(O)c(O)c1
InChI
1S/C8H8O5/c9-5-2-1-4(3-6(5)10)7(11)8(12)13/h1-3,7,9-11H,(H,12,13)
InChI key
RGHMISIYKIHAJW-UHFFFAOYSA-N
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一般描述
去甲肾上腺素的代谢物。
应用
DL-3,4-二羟基扁桃酸用于同时分析尿液中的4-羟基-3-甲氧基扁桃酸和4-羟基-3-甲氧基苯基乙酸。此外，其还被用来研究体温变化。
警示用语：
Warning
危险声明
危险分类
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官
Respiratory system
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
dust mask type N95 (US), Eyeshields, Gloves
M Kawamura et al.
Journal of the autonomic nervous system, 66(3), 145-148 (1997-12-24)
After norepinephrine (NE) is deaminated by monoamine oxidase (MAO), the aldehyde formed is either metabolized to 3,4-dihydroxy-mandelic acid (DHMA) by aldehyde dehydrogenase or is converted to 3,4-dihydroxyphenylglycol (DHPG) by aldehyde or aldose reductase. The present study examined the effects of
J Y Li et al.
Analytical biochemistry, 190(2), 354-359 (1990-11-01)
A quantitative assay for the diphenol oxidase activity of tyrosinase (EC 1.14.18.1) using high-pressure liquid chromatography with electrochemical detection is described. The assay is based on the observation (M. Sugumaran, 1986, Biochemistry 25, 4489-4492) that tyrosinase catalyzes the oxidative decarboxylation
S J Soldin et al.
Clinical chemistry, 26(2), 291-294 (1980-02-01)
We describe a rapid, reliable "high-performance" liquid-chromatographic method of simultaneously analyzing for 4-hydroxy-3-methoxymandelic acid (I) and 4-hydroxy-3-methoxyphenylacetic acid (II) in urine. Paired-ion chromatography and amperometric detection are used in the method. A 5-mL aliquot of urine is adjusted to pH
W I Cranston et al.
The Journal of physiology, 223(1), 59-67 (1972-05-01)
1. The imino-dibenzyl drugs, imipramine and desipramine, which inhibit the uptake by neurones of noradrenaline, were injected into the lateral cerebral ventricles of cats and rabbits: changes in body temperature resulted which were different for the two species, but nevertheless
Andrea E Schwaninger et al.
Toxicology letters, 202(2), 120-128 (2011-02-08)
3,4-Methylenedioxymethamphetamine (MDMA, Ecstasy) is excreted in human urine mainly as conjugates of its metabolites 3,4-dihydroxymethamphetamine (DHMA) and 4-hydroxy-3-methoxymethamphetamine (HMMA). The glucuronidation kinetics of HMMA showed high capacities, but also high K(m) values, unlikely to be reached after recreational user's doses.
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