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Merck
CN

152242

牛磺酸

99%

别名:

2-氨基乙磺酸

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线性分子式:
NH2CH2CH2SO3H
化学文摘社编号:
分子量:
125.15
EC Number:
203-483-8
UNSPSC Code:
12352103
MDL number:
Beilstein/REAXYS Number:
1751215
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assay

99%

mp

>300 °C (lit.)

SMILES string

NCCS(O)(=O)=O

InChI

1S/C2H7NO3S/c3-1-2-7(4,5)6/h1-3H2,(H,4,5,6)

InChI key

XOAAWQZATWQOTB-UHFFFAOYSA-N

Biochem/physiol Actions

甘氨酸受体的非选择性内源激动剂。
甘氨酸受体的非选择性内源激动剂。在某些细胞中调节细胞凋亡的条件必需磺化氨基酸;在许多新陈代谢活动中起作用;是蛋氨酸和半胱氨酸的代谢产物。


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George R Pettit et al.
Journal of natural products, 68(7), 974-978 (2005-07-26)
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Deniz Tasdemir et al.
Bioorganic & medicinal chemistry, 15(21), 6834-6845 (2007-09-04)
The type II fatty acid pathway (FAS-II) is a validated target for antimicrobial drug discovery. An activity-guided isolation procedure based on Plasmodium falciparum enoyl-ACP reductase (PfFabI) enzyme inhibition assay on the n-hexane-, the CHCl(3-) and the aq MeOH extracts of
Iris Thondorf et al.
Bioorganic & medicinal chemistry, 19(21), 6409-6418 (2011-10-01)
The proton-coupled amino acid transporter hPAT1 has recently gained much interest due to its ability to transport small drugs thereby allowing their oral administration. A three-dimensional quantitative structure-activity relationship (3D QSAR) study has been performed on its natural and synthetic