157481
4-硝基查耳酮
99%
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关于此项目
线性分子式:
O2NC6H4CH=CHCOC6H5
化学文摘社编号:
分子量:
253.25
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352100
EC Number:
214-949-5
MDL number:
Assay:
99%
Form:
solid
产品名称
4-硝基查耳酮, 99%
form
solid
InChI key
WDZGGAFMGIOIQS-DHZHZOJOSA-N
InChI
1S/C15H11NO3/c17-15(13-4-2-1-3-5-13)11-8-12-6-9-14(10-7-12)16(18)19/h1-11H/b11-8+
SMILES string
[O-][N+](=O)c1ccc(\C=C\C(=O)c2ccccc2)cc1
assay
99%
mp
158-160 °C (lit.)
functional group
ketone
nitro
phenyl
Application
4-Nitrochalcone was used in the synthesis of 2,3-dibromo-4-nitrochalcone.
General description
Mutagenic activity of 4-nitrochalcone on two strains of Salmonella typhimurium (TA98 and TA100) with and without rat liver microsomal and cytosolic enzymes has been tested.
存储类别
11 - Combustible Solids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
法规信息
新产品
此项目有
Synthesis and Photochromic Properties of New Heterocyclic Derivatives of 1, 3-Diazabicyclo [3.1. 0] Hex-3-Ene.
Mahmoodi NO, et al.
J. Chin. Chem. Soc., 54(3), 635-641 (2007)
K A Rashid et al.
Mutation research, 169(3), 71-79 (1986-03-01)
31 p-monosubstituted chalcones (E-1, 3-diphenylpropene-1-one) and the corresponding oxides (E-1-benzoyl-2-phenyloxirane) were tested for mutagenic activity on two strains of Salmonella typhimurium (TA98 and TA100) with and without rat liver microsomal and cytosolic enzymes. Highest mutagenicity (3.0 revertants/nmole in either strain)
João Paulo Assolini et al.
European journal of pharmacology, 884, 173392-173392 (2020-08-01)
The Leishmaniasis treatment currently available involves some difficulties, such as high toxicity, variable efficacy, high cost, therefore, it is crucial to search for new therapeutic alternatives. Over the past few years, research on new drugs has focused on the use
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