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Merck
CN

157481

4-硝基查耳酮

99%

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关于此项目

线性分子式:
O2NC6H4CH=CHCOC6H5
化学文摘社编号:
分子量:
253.25
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352100
EC Number:
214-949-5
MDL number:
Assay:
99%
Form:
solid
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assay

99%

form

solid

mp

158-160 °C (lit.)

functional group

ketone, nitro, phenyl

SMILES string

[O-][N+](=O)c1ccc(\C=C\C(=O)c2ccccc2)cc1

InChI

1S/C15H11NO3/c17-15(13-4-2-1-3-5-13)11-8-12-6-9-14(10-7-12)16(18)19/h1-11H/b11-8+

InChI key

WDZGGAFMGIOIQS-DHZHZOJOSA-N

General description

Mutagenic activity of 4-nitrochalcone on two strains of Salmonella typhimurium (TA98 and TA100) with and without rat liver microsomal and cytosolic enzymes has been tested.

Application

4-Nitrochalcone was used in the synthesis of 2,3-dibromo-4-nitrochalcone.


存储类别

11 - Combustible Solids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

法规信息

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历史批次信息供参考:

分析证书(COA)

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Synthesis and Photochromic Properties of New Heterocyclic Derivatives of 1, 3-Diazabicyclo [3.1. 0] Hex-3-Ene.
Mahmoodi NO, et al.
J. Chin. Chem. Soc., 54(3), 635-641 (2007)
K A Rashid et al.
Mutation research, 169(3), 71-79 (1986-03-01)
31 p-monosubstituted chalcones (E-1, 3-diphenylpropene-1-one) and the corresponding oxides (E-1-benzoyl-2-phenyloxirane) were tested for mutagenic activity on two strains of Salmonella typhimurium (TA98 and TA100) with and without rat liver microsomal and cytosolic enzymes. Highest mutagenicity (3.0 revertants/nmole in either strain)
João Paulo Assolini et al.
European journal of pharmacology, 884, 173392-173392 (2020-08-01)
The Leishmaniasis treatment currently available involves some difficulties, such as high toxicity, variable efficacy, high cost, therefore, it is crucial to search for new therapeutic alternatives. Over the past few years, research on new drugs has focused on the use



全球贸易项目编号

货号GTIN
157481-25G04061838743381