Quality Level
assay
98%
refractive index
n20/D 1.534 (lit.)
bp
225-226 °C (lit.)
density
1.235 g/mL at 25 °C (lit.)
functional group
acyl chloride, phenoxy
SMILES string
ClC(=O)COc1ccccc1
InChI
1S/C8H7ClO2/c9-8(10)6-11-7-4-2-1-3-5-7/h1-5H,6H2
InChI key
PKUPAJQAJXVUEK-UHFFFAOYSA-N
Application
Phenoxyacetyl chloride was used in the synthesis of:
- series of macrocyclic bis-β-lactams
- 5-phenyl-6-epiphenoxymethylpenicillin benzyl ester
- N-protected guanosine derivatives, useful in RNA synthesis
- phenyloxyketene, for cycloaddition to imines leading to β-lactams
signalword
Danger
hcodes
Hazard Classifications
Skin Corr. 1B - STOT SE 3
target_organs
Respiratory system
supp_hazards
存储类别
8A - Combustible corrosive hazardous materials
wgk
WGK 3
ppe
Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter
法规信息
新产品
此项目有
H Vanderhaeghe et al.
Journal of medicinal chemistry, 18(5), 486-490 (1975-05-01)
Cycloaddition of azidoacetyl chloride to benzyl D-5,5-dimethyl-5-phenyl-2-thiazoline-4-carboxylate (1a) gave 5-phenyl-6alpha-azidopenicillanate (2a). By catalytic reduction of 2a and reaction with phenoxyacetyl chloride, 5-phenyl-6-epiphenoxymethylpenicillin benzyl ester (4a) was obtained. Oxidation of 4a gave the sulfoxide 6, which was isomerized in the presence
Natarajan Arumugam et al.
Medicinal chemistry (Shariqah (United Arab Emirates)), 10(7), 730-737 (2014-02-27)
A series of macrocyclic bis-β-lactams has been synthesized in three good yielding steps using a Staudinger [2+2] cycloaddition reaction of ketene derived from phenoxyacetyl chloride as the key step. The reaction provided a diastereomeric mixture of cis-anti-cis (C2-symmetry) and cis-syn-cis
Tetrahedron, 63, 3380-3380 (2007)
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| 158623-10G | 04061838346285 |
| 158623-250G | 04061838744098 |
| 158623-50G | 04061838744104 |