161136
2-(3,4-二羟基苯基)乙胺 氢溴酸盐
99%
别名:
3,4-二羟基苯乙胺 氢溴酸盐, 多巴胺 氢溴酸盐
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关于此项目
线性分子式:
(HO)2C6H3CH2CH2NH2·HBr
化学文摘社编号:
分子量:
234.09
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352100
EC Number:
211-436-8
MDL number:
InChI key
SGRSNYSOAPBTJP-UHFFFAOYSA-N
InChI
1S/C8H11NO2.BrH/c9-4-3-6-1-2-7(10)8(11)5-6;/h1-2,5,10-11H,3-4,9H2;1H
SMILES string
Br.NCCc1ccc(O)c(O)c1
assay
99%
form
solid
mp
218-220 °C (lit.)
Application
3-羟基酪胺氢溴酸盐用于制备多巴胺标准品，通过快速扫描循环伏安法测量R6 / 1 HD模型小鼠纹状体脑片的多巴胺释放和吸收。将其作为内标物用于液相色谱法测定生物组织中的儿茶酚胺类物质。
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
Determination of catecholamines in biological tissues by liquid chromatography with coulometric detection.
G de Saint Blanquat et al.
Journal of chromatography, 415(2), 388-392 (1987-04-10)
Andrea N Ortiz et al.
Neuroscience letters, 492(1), 11-14 (2011-01-25)
Huntington's disease (HD) is a progressive, neurodegenerative movement disorder. Here, we used fast-scan cyclic voltammetry to measure dopamine release and uptake in striatal brain slices from R6/1 HD model mice. Peak dopamine release ([DA](max)) was significantly diminished in R6/1 mice
Azam Sargazi et al.
Colloids and surfaces. B, Biointerfaces, 171, 150-158 (2018-07-20)
Hyaluronic acid (HA) is increasingly investigated for biomedical applications such as regenerative medicine, aesthetic medicine, and drug delivery. Accordingly, conjugation of HA to PEGylated MNPs could increase the active targeting ability of nano-drug carriers toward CD44 receptors and be useful
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
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