161136
2-(3,4-二羟基苯基)乙胺 氢溴酸盐
99%
别名:
3,4-二羟基苯乙胺 氢溴酸盐, 多巴胺 氢溴酸盐
方案
99%
表单
solid
mp
218-220 °C (lit.)
SMILES字符串
Br.NCCc1ccc(O)c(O)c1
InChI
1S/C8H11NO2.BrH/c9-4-3-6-1-2-7(10)8(11)5-6;/h1-2,5,10-11H,3-4,9H2;1H
InChI key
SGRSNYSOAPBTJP-UHFFFAOYSA-N
应用
3-羟基酪胺氢溴酸盐用于制备多巴胺标准品，通过快速扫描循环伏安法测量R6 / 1 HD模型小鼠纹状体脑片的多巴胺释放和吸收。将其作为内标物用于液相色谱法测定生物组织中的儿茶酚胺类物质。
警示用语：
Warning
危险声明
危险分类
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官
Respiratory system
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
dust mask type N95 (US), Eyeshields, Gloves
Determination of catecholamines in biological tissues by liquid chromatography with coulometric detection.
G de Saint Blanquat et al.
Journal of chromatography, 415(2), 388-392 (1987-04-10)
Andrea N Ortiz et al.
Neuroscience letters, 492(1), 11-14 (2011-01-25)
Huntington's disease (HD) is a progressive, neurodegenerative movement disorder. Here, we used fast-scan cyclic voltammetry to measure dopamine release and uptake in striatal brain slices from R6/1 HD model mice. Peak dopamine release ([DA](max)) was significantly diminished in R6/1 mice
Azam Sargazi et al.
Colloids and surfaces. B, Biointerfaces, 171, 150-158 (2018-07-20)
Hyaluronic acid (HA) is increasingly investigated for biomedical applications such as regenerative medicine, aesthetic medicine, and drug delivery. Accordingly, conjugation of HA to PEGylated MNPs could increase the active targeting ability of nano-drug carriers toward CD44 receptors and be useful
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