161454
5-(4-甲基苯基)5-苯基乙内酰脲
≥99%
别名:
5-苯基-5-(对甲苯基)乙内酰脲, MPPH
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关于此项目
经验公式（希尔记法）:
C16H14N2O2
化学文摘社编号:
分子量:
266.29
UNSPSC Code:
12352100
PubChem Substance ID:
EC Number:
257-028-3
MDL number:
Assay:
≥99%
Form:
powder
InChI key
WPAPSGQWYNPWCZ-UHFFFAOYSA-N
InChI
1S/C16H14N2O2/c1-11-7-9-13(10-8-11)16(12-5-3-2-4-6-12)14(19)17-15(20)18-16/h2-10H,1H3,(H2,17,18,19,20)
SMILES string
Cc1ccc(cc1)C2(NC(=O)NC2=O)c3ccccc3
assay
≥99%
form
powder
mp
225-226 °C (lit.)
solubility
soluble 50 mg/mL, clear to slightly hazy, colorless to light yellow (DMF:HCl(2:1))
functional group
phenyl
Quality Level
Application
5-(p-Methylphenyl)-5-phenylhydantoin was used as internal standard in quantitative determination of phenytoin in brain microdialysate, saliva and blood from human samples by GC-MS method . It was used in DMD-test to determine chromatographic properties of C8- or C18-bonded phases for clinical and forensic toxicological screening.
Reactant for synthesis of N-chlorohydantoins
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Carc. 2 - Repr. 2
存储类别
13 - Non Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type P3 (EN 143) respirator cartridges
A simple test to characterise C8/C18-bonded phases, particularly for toxicological screening.
Daldrup T and Kardel B.
Chromatographia, 18(2), 81-83 (1984)
T M Hassell et al.
Epilepsia, 25(5), 556-563 (1984-10-01)
The metabolism of sodium phenytoin (PHT) in the cat was studied by gas-liquid chromatographic analyses of the drug and its metabolites extracted from plasma, urine, and feces during a 5-month course of daily oral administration. Plasma PHT levels of 15-18
Jean-Baptiste Rivière et al.
Nature genetics, 44(8), 934-940 (2012-06-26)
Megalencephaly-capillary malformation (MCAP) and megalencephaly-polymicrogyria-polydactyly-hydrocephalus (MPPH) syndromes are sporadic overgrowth disorders associated with markedly enlarged brain size and other recognizable features. We performed exome sequencing in 3 families with MCAP or MPPH, and our initial observations were confirmed in exomes
Helena Fels et al.
Forensic science international, 277, e30-e35 (2017-05-17)
In this study, two fatalities associated with the synthetic opioids AH-7921 and MT-45 are reported. Within the last few years, both compounds have emerged on the recreational drug market and are sold as "research chemicals" on the internet. In the
M Riedmann et al.
Therapeutic drug monitoring, 3(4), 397-413 (1981-01-01)
Specific antiepileptic drug (AED) concentrations in serum are believed to cause therapeutic effects in individual patients. Communication between the clinician and the laboratory performing the drug level determinations is therefore essential for safe and effective medication. The now common practice
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