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Merck
CN

163759

哌嗪-N,N′-二(2-乙磺酸)

别名:

1,4-哌嗪二乙磺酸, 哌嗪-1,4-双(2-乙磺酸), 哌嗪-N,N′-双(2-乙磺酸)

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经验公式(希尔记法):
C8H18N2O6S2
化学文摘社编号:
分子量:
302.37
EC Number:
227-057-6
UNSPSC Code:
12161700
MDL number:
Beilstein/REAXYS Number:
817713
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InChI

1S/C8H18N2O6S2/c11-17(12,13)7-5-9-1-2-10(4-3-9)6-8-18(14,15)16/h1-8H2,(H,11,12,13)(H,14,15,16)

InChI key

IHPYMWDTONKSCO-UHFFFAOYSA-N

SMILES string

OS(=O)(=O)CCN1CCN(CC1)CCS(O)(=O)=O

useful pH range

6.1-7.5

pKa (25 °C)

6.8

mp

>300 °C (lit.)

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K Hartmann et al.
Blood, 89(8), 2863-2870 (1997-04-15)
The factors that control migration of mast cells to sites of inflammation and tissue repair remain largely undefined. Whereas several recent studies have described chemotactic factors that induce migration of murine mast cells, only stem cell factor (SCF) is known
D W MacGlashan et al.
The Journal of clinical investigation, 70(4), 747-751 (1982-10-01)
Although mediator release from mast cells and basophils plays a central role in the pathogenesis of human allergic disease, biochemical studies have been restricted to rat peritoneal mast cells and basophilic leukemia cells because they could be easily purified. We
P S Baur et al.
Journal of microscopy, 109(3), 315-327 (1977-04-01)
PIPES, an organic based buffer, was used in the preparation of a variety of marine and mammalian tissues for electron microscopic study. The ultrastructural results demonstrate that this buffer renders superior ultrastructural details to those obtained with some of the
E R Swenson et al.
The American journal of physiology, 250(2 Pt 2), F288-F293 (1986-02-01)
Maximal rates of renal hydrogen ion secretion and bicarbonate reabsorption in the dogfish were stimulated by intravascular infusion of acidic and basic buffers: bicarbonate, phosphate, phenol red, dimethadione (DMO), imidazole, and piperazine-N,N'-bis(2 ethanesulfonic acid) (PIPES). There was no difference in
V D Prokopieva et al.
Alcohol and alcoholism (Oxford, Oxfordshire), 35(1), 44-48 (2000-02-24)
The effects of carnosine and related compounds on erythrocytes from alcoholics were studied. In their presence, erythrocytes showed an increased ability to resist haemolysis and showed a more normal morphology, with carnosine and N-acetyl-carnosine being the most effective compounds. These

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