171964
槲皮素 二水合物
98%
别名:
2-（3,4-二羟基苯基）-3,5,7-三羟基-4 H -1-苯并吡喃-4-酮 二水合物, 3,3′,4′,5,7-五羟基黄酮 二水合物
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关于此项目
经验公式（希尔记法）:
C15H10O7 · 2H2O
化学文摘社编号:
分子量:
338.27
EC Number:
204-187-1
UNSPSC Code:
12352103
Beilstein/REAXYS Number:
317313
Colour Index Number:
75670
assay
98%
mp
>300 °C (lit.)
SMILES string
OC(C(O)=C1)=CC=C1C2=C(O)C(C3=C(O)C=C(O)C=C3O2)=O
InChI
1S/C15H10O7.2H2O/c16-7-4-10(19)12-11(5-7)22-15(14(21)13(12)20)6-1-2-8(17)9(18)3-6;;/h1-5,16-19,21H;2*1H2
InChI key
GMGIWEZSKCNYSW-UHFFFAOYSA-N
Application
酶抑制剂。
Biochem/physiol Actions
槲皮素二水合物是具有抗癌活性的黄酮类化合物。
槲皮素二水合物是具有抗癌活性的黄酮类化合物。槲皮素为线粒体 ATP 酶和磷酸二酯酶抑制剂。它可抑制 PI3 激酶活性并且轻微抑制 PIP 激酶活性。槲皮素对癌细胞系具有抗增殖作用，通过 II 型雌激素受体降低癌细胞的生长，并且阻滞细胞周期晚期 G1 相中人类白血病 T 细胞。
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Danger
hcodes
Hazard Classifications
Acute Tox. 3 Oral
存储类别
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 1
ppe
Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
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Aik Jiang Lau et al.
Pharmacological research, 100, 64-72 (2015-08-05)
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