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Merck
CN

19079

3,4-(亚甲二氧基)苦杏仁酸

≥98.0%

别名:

α-羟基-1,3-苯并二氧杂环戊烯-5-乙酸

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关于此项目

经验公式(希尔记法):
C9H8O5
化学文摘社编号:
分子量:
196.16
EC Number:
248-628-6
UNSPSC Code:
12352100
PubChem Substance ID:
Beilstein/REAXYS Number:
209546
MDL number:
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InChI key

CLUJFRCEPFNVHW-UHFFFAOYSA-N

InChI

1S/C9H8O5/c10-8(9(11)12)5-1-2-6-7(3-5)14-4-13-6/h1-3,8,10H,4H2,(H,11,12)

SMILES string

OC(C(O)=O)c1ccc2OCOc2c1

assay

≥98.0%

form

powder

mp

158-162 °C

Application

3,4-(Methylenedioxy)mandelic acid was used as starting reagent in the synthesis of (-)cephalotaxine, (+)harringtonine and (-)drupacine.

pictograms

Exclamation mark

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Hajer Abdelkafi et al.
Natural product reports, 29(8), 845-869 (2012-06-21)
The Cephalotaxus genus belongs to the Cephalotaxaceae family of conifers. Over the past decades it has proved to be a fruitful source of interesting natural products, especially alkaloids (cephalotaxine esters) and terpenoids (abietanes, troponoids), which often display medicinal properties, especially
Anna Constance Vind et al.
Molecular cell, 78(4), 700-713 (2020-04-15)
Impairment of ribosome function activates the MAPKKK ZAK, leading to activation of mitogen-activated protein (MAP) kinases p38 and JNK and inflammatory signaling. The mechanistic basis for activation of this ribotoxic stress response (RSR) remains completely obscure. We show that the

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