191213
5-氨基乳清酸
99%
别名:
5-氨基-1,2,3,6-四氢-2,6-二氧代-4-嘧啶羧酸, 5-氨基-6-羧基-2,4-二羟基嘧啶
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关于此项目
经验公式（希尔记法）:
C5H5N3O4
化学文摘社编号:
分子量:
171.11
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352100
EC Number:
230-514-2
MDL number:
Assay:
99%
Form:
solid
InChI key
HWCXJKLFOSBVLH-UHFFFAOYSA-N
InChI
1S/C5H5N3O4/c6-1-2(4(10)11)7-5(12)8-3(1)9/h6H2,(H,10,11)(H2,7,8,9,12)
SMILES string
NC1=C(NC(=O)NC1=O)C(O)=O
assay
99%
form
solid
mp
>300 °C (lit.)
functional group
carboxylic acid
General description
5-Aminoorotic acid forms complexes with cerium (III), lanthanum (III) and neodymium (III). It reacts with dianhydride of ethylenedinitrilotetraacetic acid in dry DMF or DMSO to yield functionalized dicarboxamide derivatives.
Application
5-Aminoorotic acid was used as an internal standard during the electrochemical determination of orotic acid.
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
Irena Kostova et al.
Medicinal chemistry (Shariqah (United Arab Emirates)), 4(4), 371-378 (2008-08-05)
The cerium (III), lanthanum (III) and neodymium (III) complexes of 5-aminoorotic acid were synthesized and their structures were determined by means of theoretical study, spectral and physicochemical analysis. Significant differences in the spectra of the complexes were observed as compared
Synthesis and characterisation of chelating polycarboxylate ligands capable of forming intermolecular, complementary triple hydrogen bonds.
Georgopoulou AS, et al.
J. Chem. Soc., Dalton Trans., 11, 1869-1878 (1998)
Tommaso R I Cataldi et al.
Journal of chromatography. A, 1107(1-2), 130-138 (2006-01-13)
The application of activated pulsed amperometric detection (APAD) for the determination of orotic acid (OrA) in real samples at a gold working electrode in alkaline solutions, in combination with anion-exchange chromatography, is reported. Such an activated potential waveform was designed
Rony Panarsky et al.
Cancer & metabolism, 8, 7-7 (2020-08-11)
The loss-of-function mutation of fumarate hydratase (FH) is a driver of hereditary leiomyomatosis and renal cell carcinoma (HLRCC). Fumarate accumulation results in activation of stress-related mechanisms leading to upregulation of cell survival-related genes. To better understand how cells compensate for
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