191736
Pargyline 盐酸盐
99%
别名:
N-甲基-N-2-丙炔基苄胺 盐酸盐, N-甲基-N-丙炔基苄胺 盐酸盐
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关于此项目
线性分子式:
C6H5CH2N(CH3)CH2C≡CH·HCl
化学文摘社编号:
分子量:
195.69
EC Number:
206-175-1
UNSPSC Code:
12352103
PubChem Substance ID:
Beilstein/REAXYS Number:
3699487
MDL number:
assay
99%
mp
160-163 °C (lit.)
SMILES string
Cl[H].CN(CC#C)Cc1ccccc1
InChI
1S/C11H13N.ClH/c1-3-9-12(2)10-11-7-5-4-6-8-11;/h1,4-8H,9-10H2,2H3;1H
InChI key
BCXCABRDBBWWGY-UHFFFAOYSA-N
Gene Information
human ... MAOA(4128), MAOB(4129)
Biochem/physiol Actions
选择性 MAO-B 抑制剂。
法规信息
新产品
此项目有
Masahiro Yoshida et al.
The Journal of organic chemistry, 78(4), 1687-1692 (2013-02-01)
The reaction of propargylic carbonates with 4-hydroxy-2-pyrones in the presence of a palladium catalyst is described. By the choice of the reaction temperature, two types of the substituted furo[3,2-c]pyran-4-one derivatives were regioselectively synthesized, respectively.
Shauna N Vasilatos et al.
Carcinogenesis, 34(6), 1196-1207 (2013-01-29)
Our previous studies demonstrated that lysine-specific demethylase 1 (LSD1) and histone deacetylases (HDACs) closely interact in controlling growth of breast cancer cells. However, the underlying mechanisms are largely unknown. In this study, we showed that knockdown of LSD1 expression (LSD1-KD)
Avanashiappan Nandakumar et al.
Organic letters, 15(2), 382-385 (2013-01-12)
Tetrasubstituted olefin based new xanthene derivatives have been synthesized via palladium-catalyzed carbopalladation/C-H activation of 2-bromobenzyl-N-propargylamine derivatives. The synthesized compounds display a pronounced solid state fluorescence due to their restricted internal rotation of a C-Ar bond in the solid or aggregation