199486
2-溴-2′,4′-二甲氧基苯乙酮
96%
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关于此项目
线性分子式:
(CH3O)2C6H3COCH2Br
化学文摘社编号:
分子量:
259.10
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352100
EC Number:
262-542-6
MDL number:
Assay:
96%
Form:
powder
InChI key
PKVBZABQCCQHLD-UHFFFAOYSA-N
InChI
1S/C10H11BrO3/c1-13-7-3-4-8(9(12)6-11)10(5-7)14-2/h3-5H,6H2,1-2H3
SMILES string
COc1ccc(C(=O)CBr)c(OC)c1
assay
96%
form
powder
mp
102-104 °C (lit.)
General description
2-Bromo-2′,4′-dimethoxyacetophenone inhibited the activity of papain.
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
P I Clark et al.
European journal of biochemistry, 84(1), 293-299 (1978-03-01)
Photolysis of papain which had been inhibited with 2-bromo-2',4'-dimethoxyacetophenone regenerated papain, but also formed [deltaSer25]-papain (i.e. papain in which the active-site cysteine residue 25 was replaced by dehydroserine) via the intermediate dehydrocysteine analogue, [deltaCys25]-papain. Reduction with sodium borohydride gave [Ser25]papain.
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