20423
(叔丁氧基羰基甲基)氯化三苯基磷
≥98.0%
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关于此项目
线性分子式:
(CH3)3COCOCH2P+(C6H5)3Cl
化学文摘社编号:
分子量:
412.89
Beilstein:
4116684
MDL编号:
UNSPSC代码:
12352108
PubChem化学物质编号:
NACRES:
NA.22
方案
≥98.0%
表单
solid
反应适用性
reaction type: C-C Bond Formation
SMILES字符串
[Cl-].CC(C)(C)OC(=O)C[P+](c1ccccc1)(c2ccccc2)c3ccccc3
InChI
1S/C24H26O2P.ClH/c1-24(2,3)26-23(25)19-27(20-13-7-4-8-14-20,21-15-9-5-10-16-21)22-17-11-6-12-18-22;/h4-18H,19H2,1-3H3;1H/q+1;/p-1
InChI key
PWEGQXPODNSKMU-UHFFFAOYSA-M
应用
Reactant for:
- Stereoselective preparation of (arylamino)quinazoline derivatives bearing tethered acrylamide moieties as inhibitors of epidermal growth factor receptor and histone deacetylase
- Thermal decomposition reactions
其他说明
用于 Wittig 反应的试剂;也可用于合成 α-重氮磷盐
警示用语:
Warning
危险声明
危险分类
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官
Respiratory system
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
dust mask type N95 (US), Eyeshields, Gloves
法规信息
新产品
此项目有
M. Regitz et al.
Liebigs Ann. Chem., 1865-1865 (1981)
B.B. Snider et al.
Journal of the American Chemical Society, 101, 6023-6023 (1978)
M.P. Cooke et al.
The Journal of Organic Chemistry, 47, 4955-4955 (1982)
Rhushikesh A Kulkarni et al.
Nature chemical biology, 15(4), 391-400 (2019-02-06)
Hereditary cancer disorders often provide an important window into novel mechanisms supporting tumor growth. Understanding these mechanisms thus represents a vital goal. Toward this goal, here we report a chemoproteomic map of fumarate, a covalent oncometabolite whose accumulation marks the
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