General description
磺酰胺,一种与格氏试剂相容的极性非质子溶剂,可用作医学化学中的官能团。
Application
磺胺被用于合成以下物质:
- ArCH=NSO2NH2型席夫碱
- 1H,3H-2,1,3-苯并噻二嗪-4-酮-2,2-二氧化物(BTDD)
- 在一项PPARα激活的研究中,合成油酰乙醇胺类似物的磺酰胺类似物。
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signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
Anomeric effects in sulfamides
Eric H et al.
The Journal of Physical Chemistry A, 120, 3677-3682 (2016)
Sulfamides and sulfonamides as polar aprotic solvents
Herman R G et al.
The Journal of Organic Chemistry, 52, 479-483 (1987)
A Scozzafava et al.
Journal of enzyme inhibition, 15(5), 443-453 (2000-10-13)
Sulfamide and sulfamic acid are the simplest compounds containing the SO2NH2 moiety, responsible for binding to the Zn(II) ion within carbonic anhydrase (CA, EC 4.2.1.1) active site, and thus acting as inhibitors of the many CA isozymes presently known. Here
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| 211370-25G | 04061832418872 |
| 211370-5G | 04061838771773 |
