212970
2-(溴甲基)丙烯酸
98%
别名:
α-(Bromomethyl)acrylic acid, 2-(Bromomethyl)-2-propenoic acid, Bromomethylacrylic acid
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关于此项目
线性分子式:
CH2=C(CH2Br)COOH
化学文摘社编号:
分子量:
164.99
UNSPSC Code:
12162002
NACRES:
NA.23
PubChem Substance ID:
EC Number:
276-774-0
Beilstein/REAXYS Number:
2426204
MDL number:
产品名称
2-(溴甲基)丙烯酸, 98%
InChI key
NOOYFQLPKUQDNE-UHFFFAOYSA-N
InChI
1S/C4H5BrO2/c1-3(2-5)4(6)7/h1-2H2,(H,6,7)
SMILES string
OC(=O)C(=C)CBr
assay
98%
form
solid
mp
70-73 °C (lit.)
storage temp.
2-8°C
Quality Level
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Application
可与醛和酮反应生成 α-亚甲基-丁内酯。用于合成甲氨蝶呤类似物。
signalword
Danger
hcodes
Hazard Classifications
Skin Corr. 1B
存储类别
8A - Combustible corrosive hazardous materials
wgk
WGK 3
ppe
Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges
A Abraham et al.
Journal of medicinal chemistry, 34(1), 222-227 (1991-01-01)
Five analogues of methotrextate (MTX), 10-deazaaminopterin (10-DAM), and 10-ethyl-10-deazaaminopterin (10-EDAM) in which the glutamate moiety was replaced by either a gamma-methyleneglutamate or beta-hydroxyglutamate were synthesized and evaluated for their antifolate activity. These analogous are 4-amino-4-deoxy-N10-methylpteroyl-beta-hydroxyglutamic acid (1), 4-amino-4-deoxy-10-deazapteroyl-beta-hydroxyglutamic acid (2)
Synthesis, 530-530 (1990)
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