22490
白屈氨酸 水合物
≥97.0% (dried material, T), ~1 mol/mol water
别名:
4-氧代-1,4-二氢-2,6-吡啶二甲酸 水合物, 4-羟基吡啶-2,6-二羧酸
方案
≥97.0% (dried material, T)
表单
powder
杂质
~1 mol/mol water
mp
267 °C (dec.) (lit.)
官能团
carboxylic acid
SMILES字符串
O.OC(=O)C1=CC(=O)C=C(N1)C(O)=O
InChI
1S/C7H5NO5.H2O/c9-3-1-4(6(10)11)8-5(2-3)7(12)13;/h1-2H,(H,8,9)(H,10,11)(H,12,13);1H2
InChI key
SNGPHFVJWBKEDG-UHFFFAOYSA-N
正在寻找类似产品? 访问 产品对比指南
应用
Chelidamic acid hydrate was used in the synthesis of 4-Chloro-N,N,N′,N′-tetraethylpyridine-2,6-dicarboxamide.
生化/生理作用
其属于最有效的“构象受限的谷氨酸类似物”，是谷氨酸脱羧酶抑制剂。
警示用语：
Warning
危险声明
危险分类
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官
Respiratory system
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
dust mask type N95 (US), Eyeshields, Gloves
Anne-Sophie Chauvin et al.
Organic & biomolecular chemistry, 1(4), 737-740 (2003-08-22)
The synthesis of 4-substituted dipicolinic acid derivatives requiring palladium catalysis is described. A keto-enol equilibrium has been observed, depending on the nature of the 2,6-position substituents.
[Use of the radial hemolysis reaction for titrating antirabies sera].
G N Zgurskaia et al.
Voprosy virusologii, 29(3), 360-361 (1984-05-01)
Maya Tutughamiarso et al.
Acta crystallographica. Section C, Crystal structure communications, 68(Pt 9), o344-o350 (2012-09-01)
Different tautomeric and zwitterionic forms of chelidamic acid (4-hydroxypyridine-2,6-dicarboxylic acid) are present in the crystal structures of chelidamic acid methanol monosolvate, C(7)H(5)NO(5)·CH(4)O, (Ia), dimethylammonium chelidamate (dimethylammonium 6-carboxy-4-hydroxypyridine-2-carboxylate), C(2)H(8)N(+)·C(7)H(4)NO(5)(-), (Ib), and chelidamic acid dimethyl sulfoxide monosolvate, C(7)H(5)NO(5)·C(2)H(6)OS, (Ic). While the zwitterionic
Elvir Ramić et al.
The journal of physical chemistry. B, 110(41), 20655-20663 (2006-10-13)
Multifrequency electron paramagnetic resonance (EPR) and electron nuclear double resonance (ENDOR) techniques were used to obtain structural information about the copper(II)-chelidamate complex. Well-resolved nitrogen ENDOR spectra could be recorded from solid solution samples by using selective excitation of spin packets.
M Searcey et al.
Anti-cancer drug design, 13(8), 837-855 (1999-05-21)
We have explored the potential antitumour activity of DNA-intercalating free radical generators based on compounds constructed from 9-anilinoacridine and chelidamic acid as an iron (II) binding centre. Here we describe their synthesis, DNA cleaving ability and activity against a panel
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系客户支持