225436
2,4-二氯-6-硝基苯酚
≥95%
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关于此项目
线性分子式:
Cl2C6H2(NO2)OH
化学文摘社编号:
分子量:
208.00
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
210-202-2
Beilstein/REAXYS Number:
2050081
MDL number:
InChI key
LYPMXMBQPXPNIQ-UHFFFAOYSA-N
InChI
1S/C6H3Cl2NO3/c7-3-1-4(8)6(10)5(2-3)9(11)12/h1-2,10H
SMILES string
Oc1c(Cl)cc(Cl)cc1[N+]([O-])=O
assay
≥95%
form
crystals
contains
20% water
mp
118-120 °C (lit.)
General description
The FT-Raman and FTIR spectra of 2,4-dichloro-6-nitrophenol (2,4-DC6NP) was studied.
Application
2,4-Dichloro-6-nitrophenol, a specific inhibitor of sulfotransferases, was used to reduce the neosynthesis of [3H] pregnenolone sulfate (Δ5PS) and [3H]dehydroepiandrosterone sulfate (DHEAS).
Physical form
潮湿固体
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Eye Irrit. 2
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
法规信息
新产品
此项目有
N Sundaraganesan et al.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 65(5), 1053-1062 (2006-05-24)
The FTIR and FT-Raman spectra of 2,4-dichloro-6-nitrophenol (2,4-DC6NP) has been recorded in the region 4000-400 cm(-1) and 3500-100 cm(-1), respectively. The optimized geometry, frequency and intensity of the vibrational bands of (2,4-DC6NP) were obtained by the ab initio and DFT
D Beaujean et al.
Journal of neurochemistry, 72(2), 848-857 (1999-02-04)
Biosynthesis of the neuroactive steroids pregnenolone sulfate (delta5PS) and dehydroepiandrosterone sulfate (DHEAS) is catalyzed by the enzyme hydroxysteroid sulfotransferase (HST), which transfers the sulfonate moiety from 3'-phosphoadenosine 5'-phosphosulfate (PAPS) on the 3-hydroxy site of steroids. Although high concentrations of delta5PS
Tilman Pfeffer et al.
The Journal of pharmacology and experimental therapeutics, 375(3), 478-487 (2020-10-07)
The lysyl hydroxylases (procollagen-lysine 5-dioxygenases) PLOD1, PLOD2, and PLOD3 have been proposed as pathogenic mediators of stunted lung development in bronchopulmonary dysplasia (BPD), a common complication of preterm birth. In affected infants, pulmonary oxygen toxicity stunts lung development. Mice lacking
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