225517
甲氧基胺 盐酸盐 溶液
25-30 wt. % in H2O
别名:
O-甲胲 盐酸盐
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线性分子式:
CH3ONH2 · HCl
化学文摘社编号:
分子量:
83.52
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
3589723
Form:
liquid
InChI
1S/CH5NO.ClH/c1-3-2;/h2H2,1H3;1H
SMILES string
Cl[H].CON
InChI key
XNXVOSBNFZWHBV-UHFFFAOYSA-N
form
liquid
concentration
25-30 wt. % in H2O
refractive index
n20/D 1.4021
solubility
alcohol: soluble(lit.), water: soluble(lit.)
density
1.1 g/mL at 25 °C
Quality Level
Application
Methoxylamine hydrochloride was used as an derivatization agent during the structural investigation of novel epoxyisoprostane phospholipid in mildly oxidized low density lipoprotien.
signalword
Danger
Hazard Classifications
Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Carc. 2 - Eye Dam. 1 - Skin Corr. 1 - Skin Sens. 1 - STOT RE 1
存储类别
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter
法规信息
危险化学品
此项目有
A D Watson et al.
The Journal of biological chemistry, 274(35), 24787-24798 (1999-08-24)
One of the earliest steps in the development of the atherosclerotic lesion is the accumulation of monocyte/macrophages within the vessel wall. Oxidized lipids present in minimally modified-low density lipoproteins (MM-LDL) contribute to this process by activating endothelial cells to express
Timothy J Kinsella
Clinical cancer research : an official journal of the American Association for Cancer Research, 15(6), 1853-1859 (2009-02-26)
DNA damage processing by mismatch repair (MMR) and/or base excision repair (BER) can determine the therapeutic index following treatment of human cancers using radiation therapy and several classes of chemotherapy drugs. Over the last decade, basic and translational cancer research
Yanlin Jiang et al.
DNA repair, 8(11), 1273-1282 (2009-09-04)
Oxidative DNA damage has been implicated in a number of central nervous system pathologies. The base excision repair (BER) pathway is one of the most important cellular protection mechanisms that respond to oxidative DNA damage. Human apurinic (apyrimidinic) endonuclease/redox effector
Eva M Goellner et al.
Cancer research, 71(6), 2308-2317 (2011-03-17)
Glioblastoma multiforme (GBM) is a devastating brain tumor with poor prognosis and low median survival time. Standard treatment includes radiation and chemotherapy with the DNA alkylating agent temozolomide (TMZ). However, a large percentage of tumors are resistant to the cytotoxic
April M Luke et al.
Mutation research, 694(1-2), 65-71 (2010-09-21)
Single strand breaks (SSBs) are one of the most frequent DNA lesions caused by endogenous and exogenous agents. The most utilized alkaline-based assays for SSB detection frequently give false positive results due to the presence of alkali-labile sites that are
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