227935
天青B
prepared by direct synthesis
别名:
N,N,N′-三甲基硫堇, 亚甲基天青, 天青I
方案
>85.0% (HPLC)
表单
powder
mp
205-210 °C (dec.) (lit.)
溶解性
water: 1 mg/mL, blue to very deep blue
λmax
648 nm
ε (消光系数)
≥13000 at 241-247 nm
≥36000 at 287-293 nm
≥67000 at 638-644 nm
应用
diagnostic assay manufacturing
hematology
histology
储存温度
room temp
SMILES字符串
C[N+](C)=C(C=C1)C=C(C1=N2)SC3=C2C=CC(NC)=C3.[Cl-]
InChI
1S/C15H15N3S.ClH/c1-16-10-4-6-12-14(8-10)19-15-9-11(18(2)3)5-7-13(15)17-12;/h4-9H,1-3H3;1H
InChI key
DNDJEIWCTMMZBX-UHFFFAOYSA-N
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应用
天青B已用于M′Fadyean染色，用于炭疽杆菌( Bacillus anthracis)荚膜的染色观察。
生化/生理作用
天青B是一种阳离子染料，作为瑞氏染色剂(Romanowsky stain)的一部分，可用于血涂片染色。也可用于核酸和木质素的定位显色。
警示用语：
Warning
危险声明
危险分类
Acute Tox. 4 Oral
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
U.S. Forest Service research note FPL (1964)
A simple, reliable M'Fadyean stain for visualizing the Bacillus anthracis capsule
Owen MP
Journal of Microbiological Methods, 92, 264-269 (2013)
Barbara J. Bain, Imelda Bates, Mike A Laffan
Dacie and Lewis Practical Haematology (2016)
M Wilson et al.
Current microbiology, 25(2), 77-81 (1992-08-01)
Twenty-seven compounds were screened for their ability to sensitize Streptococcus sanguis to killing by light from a 7.3-mW Helium/Neon (HeNe) laser. Bacteria were mixed with various concentrations of the test compounds, spread over the surfaces of agar plates, and then
André Aguiar et al.
Chemosphere, 66(5), 947-954 (2006-07-15)
Several phenol derivatives were evaluated regarding their capacities for Fe(3+) and Cu(2+) reduction. Selected compounds were assayed in Fenton-like reactions to degrade Azure B. 3,4-Dihydroxyphenylacetic, 2,5-dihydroxyterephtalic, gallic, chromotropic and 3-hydroxyanthranilic acids were the most efficient reducers of both metallic ions.
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