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Merck
CN

232599

甲氧基乙酸乙酯

97%

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关于此项目

线性分子式:
CH3OCH2COOC2H5
化学文摘社编号:
分子量:
118.13
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
223-521-7
Beilstein/REAXYS Number:
1744761
MDL number:
Assay:
97%
Form:
liquid
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Quality Level

assay

97%

form

liquid

refractive index

n20/D 1.401 (lit.)

bp

44-45.5 °C/9 mmHg (lit.)

density

1.007 g/mL at 25 °C (lit.)

functional group

ester, ether

SMILES string

CCOC(=O)COC

InChI

1S/C5H10O3/c1-3-8-5(6)4-7-2/h3-4H2,1-2H3

InChI key

JLEKJZUYWFJPMB-UHFFFAOYSA-N

Application

Ethyl methoxyacetate was used:
  • as acyl donor during the preparation of enantiomers of several phenylethylamines
  • as acylation reagent for the aminolysis of 1-phenylethanamine
  • in an industrial, lipase-catalysed kinetic resolution of primary amine


pictograms

Flame

signalword

Warning

hcodes

Hazard Classifications

Flam. Liq. 3

存储类别

3 - Flammable liquids

wgk

WGK 3

flash_point_f

114.8 °F - closed cup

flash_point_c

46 °C - closed cup

ppe

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

法规信息

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历史批次信息供参考:

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Ulf Hanefeld
Organic & biomolecular chemistry, 1(14), 2405-2415 (2003-09-06)
Commonly, hydrolase-catalysed reactions are used for kinetic resolutions of alcohols, amines and acids. Only a few applications in total syntheses have been described. Most of these examples are for the synthesis of amides and peptides. Here, the synthesis of all
Lourdes Muñoz et al.
Organic & biomolecular chemistry, 9(23), 8171-8177 (2011-10-06)
Both enantiomers of several phenylethylamines, structurally related to amphetamine, have been prepared in good yields and excellent enantiomeric purity by enzymatic kinetic resolution using CAL-B and ethyl methoxyacetate as the acyl donor. In the case of the 4-hydroxyderivative of amphetamine
A Basler
Mutation research, 174(1), 11-13 (1986-05-01)
Chinese hamsters were exposed to acetone, methyl ethyl ketone, ethyl acetate and 2-methoxy ethyl acetate, known to be strong inducers of aneuploidy in the yeast Saccharomyces cerevisiae. All solvents yielded negative results in the micronucleus test, whereas the vinca alkaloid



全球贸易项目编号

货号GTIN
232599-50G04061836683306
232599-10G04061836675110