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Merck
CN

233951

亚甲基二膦酸

98%

别名:

MDP, 亚甲磷酸

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线性分子式:
CH2[P(O)(OH)2]2
化学文摘社编号:
分子量:
176.00
UNSPSC Code:
12352100
Beilstein/REAXYS Number:
1708494
MDL number:
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assay

98%

impurities

<0.5% methyl alcohol, 1% ethyl alcohol

mp

197-199 °C (lit.)

SMILES string

OP(O)(=O)CP(O)(O)=O

InChI

1S/CH6O6P2/c2-8(3,4)1-9(5,6)7/h1H2,(H2,2,3,4)(H2,5,6,7)

InChI key

MBKDYNNUVRNNRF-UHFFFAOYSA-N

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Marie R Webster et al.
Journal of medicinal chemistry, 54(19), 6647-6656 (2011-08-26)
Bisphoshonates are used clinically to treat disorders of calcium metabolism, hypercalcemia and osteoporosis, and malignant bone disease. Although these agents are commonly used in cancer patients and have potential direct anticancer effects, their use for the treatment of extraskeletal disease
Jean-Yves Winum et al.
Bioorganic & medicinal chemistry letters, 15(6), 1683-1686 (2005-03-05)
The interaction of five human carbonic anhydrase (hCA, EC 4.2.1.1) isozymes, that is, hCA I, II, IV, V, and IX with a small library of phosphonic acids/organic phosphates, including methylphosphonic acid, MPA; phenylphosphonic acid, PPA; N-(phosphonoacetyl)-L-aspartic acid, PALA, methylene diphosphonic
Scott A Lujan et al.
Proceedings of the National Academy of Sciences of the United States of America, 104(30), 12282-12287 (2007-07-17)
Conjugative transfer of plasmid DNA via close cell-cell junctions is the main route by which antibiotic resistance genes spread between bacterial strains. Relaxases are essential for conjugative transfer and act by cleaving DNA strands and forming covalent phosphotyrosine linkages. Based

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