方案
98%
mp
232-235 °C (lit.)
SMILES字符串
[Na+].CCCCCCCC\C=C/CCCCCCCC([O-])=O
InChI
1S/C18H34O2.Na/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18(19)20;/h9-10H,2-8,11-17H2,1H3,(H,19,20);/q;+1/p-1/b10-9-;
InChI key
BCKXLBQYZLBQEK-KVVVOXFISA-M
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应用
油酸被用于研究其对体外培养细胞载脂蛋白B合成、降解和分泌的影响。
生化/生理作用
油酸可增加肝细胞系和小鼠的载脂蛋白B100的分泌 。油酸在较高的生理剂量下可抑制载脂蛋白B100的分泌 。
激活肝细胞中的蛋白激酶 C。
法规信息
新产品
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Gisela Bevilacqua Rolfsen Ferreira da Silva et al.
Pharmaceutical development and technology, 23(2), 151-157 (2017-06-02)
Microemulsions (MEs) loaded with methyl dihydrojasmonate (MJ) were developed to improve the aqueous solubility of this drug. The composition of the formulations ranged according to the oil/surfactant ratio (O/S). The MEs were characterized according to diameter of droplets, X-ray diffraction
Rie Ouchi et al.
Cell metabolism, 30(2), 374-384 (2019-06-04)
Human organoid systems recapitulate in vivo organ architecture yet fail to capture complex pathologies such as inflammation and fibrosis. Here, using 11 different healthy and diseased pluripotent stem cell lines, we developed a reproducible method to derive multi-cellular human liver organoids
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