235210
(1R,2S)-(-)-N-甲基麻黄碱
99%
别名:
(-)-(1R,2S)-2-二甲基氨基-1-苯丙醇, (-)-N-甲基麻黄碱, [R-(R*,S*)]-α-[1-(二甲基氨基)乙基]苯甲醇
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关于此项目
线性分子式:
C6H5CH(OH)CH(CH3)N(CH3)2
化学文摘社编号:
分子量:
179.26
Beilstein:
3031197
EC 号:
MDL编号:
UNSPSC代码:
12352116
PubChem化学物质编号:
NACRES:
NA.22
方案
99%
表单
solid
旋光性
[α]21/D −29.2°, c = 5 in methanol
mp
86-88 °C (lit.)
官能团
amine
hydroxyl
phenyl
储存温度
2-8°C
SMILES字符串
C[C@@H]([C@H](O)c1ccccc1)N(C)C
InChI
1S/C11H17NO/c1-9(12(2)3)11(13)10-7-5-4-6-8-10/h4-9,11,13H,1-3H3/t9-,11-/m0/s1
InChI key
FMCGSUUBYTWNDP-ONGXEEELSA-N
应用
拆分剂。手性支持电解质的前体、相转移催化剂和还原剂。
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
dust mask type N95 (US), Eyeshields, Gloves
法规信息
新产品
此项目有
Angewandte Chemie (International Edition in English), 23, 165-165 (1984)
Chemistry Letters (Jpn), 981-981 (1980)
María José Ojeda-Montes et al.
Future medicinal chemistry, 9(18), 2129-2146 (2017-11-28)
Extracts from Ephedra species have been reported to be effective as antidiabetics. A previous in silico study predicted that ephedrine and five ephedrine derivatives could contribute to the described antidiabetic effect of Ephedra extracts by inhibiting dipeptidyl peptidase IV (DPP-IV).
Guoyi Ma et al.
The Journal of pharmacology and experimental therapeutics, 322(1), 214-221 (2007-04-05)
Ephedra species of plants have both beneficial and adverse effects primarily associated with the presence of ephedrine alkaloids. Few reports have appeared that examine the direct actions of ephedrine alkaloids on human subtypes of adrenergic receptors (ARs). In the present
H J Lee et al.
Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology, 30(6), 563-566 (2010-08-13)
No information is currently available on the safety of methylephedrine, a component of various cold medications available in South Korea. With previous approval by an Institutional Review Board, 349 women inadvertently exposed to methylephedrine during the 1st trimester of pregnancy
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