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经验公式(希尔记法):
C10H7ClO2S
化学文摘社编号:
分子量:
226.68
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
201-609-6
Beilstein/REAXYS Number:
2099333
MDL number:
Assay:
97%
InChI key
DASJFYAPNPUBGG-UHFFFAOYSA-N
InChI
1S/C10H7ClO2S/c11-14(12,13)10-7-3-5-8-4-1-2-6-9(8)10/h1-7H
SMILES string
ClS(=O)(=O)c1cccc2ccccc12
assay
97%
bp
194-195 °C/13 mmHg (lit.)
Quality Level
solubility
chloroform: soluble 25 mg/mL, clear to very slightly hazy, colorless to yellow
General description
1-Naphthalenesulfonyl chloride undergoes desulfitative carbonylative Stille cross-coupling reaction with tinglucal derivative.
Application
1-Naphthalenesulfonyl chloride has been used in the preparation of:
- 5′-O-naphthaleneiulfonyldeoxyuridine
- 1-sulfonylindazole derivatives
signalword
Danger
hcodes
Hazard Classifications
Eye Dam. 1 - Skin Corr. 1B
存储类别
8A - Combustible corrosive hazardous materials
wgk
WGK 3
ppe
Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges
法规信息
新产品
此项目有
A simple method for the synthesis of O2, 5′-cyclodeoxyuridine.
Tang SS and Roth JS.
Tetrahedron Letters, 9(17), 2123-2125 (1968)
Aryl and arylmethyl C-glycosides through desulfitative stille and carbonylative stille cross-coupling of tinglycals and sulfonyl chlorides.
Dubbaka SR, et al.
Synlett, 2004(07), 1235-1238 (2004)
Kevin G Liu et al.
Bioorganic & medicinal chemistry letters, 19(9), 2413-2415 (2009-04-07)
As part of our continuing efforts to identify therapeutics for CNS diseases, such as schizophrenia and Alzheimer's disease (AD), we have been focused on the 5-HT(6) receptor in an attempt to identify ligands as a potential treatment for cognitive dysfunction.
Alaa Khedr et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 1160, 122383-122383 (2020-09-20)
A sensitive liquid chromatography-tandem mass spectrometry (LC-MS) method was developed for the screening of five β-blockers (BBs), including atenolol, metoprolol, bisoprolol, propranolol, and betaxolol, in rabbit plasma. An inhouse prepared hydrazonoyl chloride compound (UOSA54) and dansyl chloride (DNS) were successfully
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