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Merck
CN

238198

马来酸二甲酯

96%

别名:

(2Z)-2-丁烯二酸二甲酯, (Z)-2-丁烯二酸二甲酯

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线性分子式:
CH3OCOCH=CHCOOCH3
化学文摘社编号:
分子量:
144.13
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
210-848-5
Beilstein/REAXYS Number:
471705
MDL number:
Assay:
96%
Form:
liquid
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产品名称

马来酸二甲酯, 96%

InChI key

LDCRTTXIJACKKU-ARJAWSKDSA-N

InChI

1S/C6H8O4/c1-9-5(7)3-4-6(8)10-2/h3-4H,1-2H3/b4-3-

SMILES string

[H]\C(=C(/[H])C(=O)OC)C(=O)OC

assay

96%

form

liquid

impurities

≤4% dimethyl fumarate

refractive index

n20/D 1.441 (lit.)

bp

204-205 °C (lit.)

solubility

water: soluble 77.9 g/L at 20 °C

density

1.152 g/mL at 25 °C (lit.)

functional group

ester

Quality Level

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Application

  • 通过与2,3-二甲基马来酸酐的可逆缩合实现的牛6S 羧肽酶原A的解离:亚基III部分表征的应用:该研究探索了采用2,3-二甲基马来酸酐实现牛6S 羧肽酶原A的解离,重点介绍了其在酶亚基部分表征中的应用。该研究显示了二甲基马来酯衍生物在蛋白质化学和酶结构研究中的潜力。(Puigserver and Desnuelle, 1975)。

General description

马来酸二甲酯是一种二烯亲和物,可用作合成二烯、塑料和共聚物的化学中间体。

马来酸二甲酯 (DMM) 是一种具有反应活性的二烯亲和物,可与取代呋喃进行超声波辅助Diels-Alder 反应。研究人员已经报道过,DMM 可通过介孔硅SBA-15-负载 Cu催化的气相氢解来合成1,4-丁二醇。据报道氯化铝可以加速DMM 和蒽的Diels-Alder反应。DMM 可通过马来酸酐、硫酸和甲醇的酯化反应合成。

pictograms

Skull and crossbonesHealth hazard

signalword

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Sens. 1 - STOT RE 2 Dermal - STOT SE 3

target_organs

Respiratory system, Skin

存储类别

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 1

flash_point_f

203.0 °F - closed cup

flash_point_c

95 °C - closed cup

ppe

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter


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M Wong et al.
Teratology, 40(2), 127-141 (1989-08-01)
The teratogenicity of phenytoin may result from its enzymatic bioactivation to a reactive intermediate, which, if not detoxified, can interact with embryonic tissues and alter development. Glutathione (GSH) is an important cofactor/substrate for many physiological processes and for the detoxification
Preparation of Cu/SBA-15 catalysts by different methods for the hydrogenolysis of dimethyl maleate to 1, 4-butanediol.
Chen L-F, et al.
Applied Catalysis A: General, 356(2), 129-136 (2009)
Synthesis and characterization of 1, 2-dicarboxyethyl-terminated polystyrene.
Zhong XF and Eisenberg A.
Macromolecules, 27(18), 4914-4918 (1994)
Bo Reum Lee et al.
Chemical communications (Cambridge, England), 47(13), 3852-3854 (2011-02-16)
We report charge-switching ionic nanocomplexes comprised of glycol chitosan grafted with 2,3-dimethylmaleic acid (DMA) (denoted as 'GCS-g-DMA' hereafter) and a proapoptotic peptide. This system allowed for improved peptide delivery to tumor sites via a mechanism of selective peptide release when
Michele Di Foggia et al.
International journal of biological macromolecules, 167, 620-632 (2020-12-07)
Many restoring formulations for damaged hair keratin have been developed. Some patents claim that the hair repair occurs through the reconstruction of disulfide bridges of keratin, through α,β-unsaturated Michael acceptors, such as shikimic acid and bis-aminopropyl diglycol dimaleate. To gain

商品

The Diels–Alder reaction is the reaction between a conjugated diene and an alkene (dienophile) to form unsaturated six-membered rings. It is also referred to as a cycloaddition.

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