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244309

β-咔啉-3-羧酸乙酯

Name: β-咔啉-3-羧酸乙酯
Brand: ALDRICH

97%

别名:

β-CCE, 9H-吡啶并[3,4-b]吲哚-3-羧酸乙酯

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关于此项目

经验公式（希尔记法）:

C₁₄H₁₂N₂O₂

化学文摘社编号:

74214-62-3

分子量:

240.26

NACRES:

NA.22

PubChem Substance ID:

24854665

UNSPSC Code:

12352100

MDL number:

MFCD00009730

Assay:

97%

Form:

solid

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属性

assay

97%

form

solid

mp

228-230 °C (lit.)

functional group

ester

SMILES string

CCOC(=O)c1cc2c(cn1)[nH]c3ccccc23

InChI

1S/C14H12N2O2/c1-2-18-14(17)12-7-10-9-5-3-4-6-11(9)16-13(10)8-15-12/h3-8,16H,2H2,1H3

InChI key

KOVRZNUMIKACTB-UHFFFAOYSA-N

Gene Information

human ... GABRA1(2554), GABRA2(2555), GABRA3(2556), GABRA5(2558), GABRG2(2566)
rat ... Gabra2(29706)

说明

pictograms

GHS07

signalword

Warning

hcodes

H315,H319,H335

pcodes

P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

法规信息

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Effects of negative allosteric modulators of gamma-aminobutyric acidA receptors on complex behavioral processes in monkeys.

J Auta et al.

The Journal of pharmacology and experimental therapeutics, 280(1), 316-325 (1997-01-01)

A multiple schedule of repeated acquisition and performance of conditional discriminations was used to characterize the effects of two negative allosteric modulators of the gamma-aminobutyric acid (GABAA) receptor (ethyl beta-carboline-3-carboxylate [beta-CCE] and N-methyl-beta-carboline-3-carboxamide [FG-7142]), a hallucinogenic beta-carboline derivative (harmine), a

Interactions of ethyl-beta-carboline-3-carboxylate and Ro 15-1788 with CGS 8216 in an animal model of anxiety.

S E File et al.

Neuroscience letters, 39(1), 91-94 (1983-08-19)

The effect of CGS 8216 (10 mg/kg) alone and in combination with the imidazodiazepine Ro 15-1788 (10 mg/kg) or ethyl-beta-carboline-3-carboxylate (beta-CCE 1 mg/kg) was tested in the social interaction test of anxiety. All 3 compounds were found to have an

Effects of beta-CCE on retention of aversively- and appetitively-motivated tasks in rats.

L J Wichlinski et al.

Physiology & behavior, 60(4), 1121-1124 (1996-10-01)

Beta-carboline-3-carboxylic acid ethyl ester (beta-CCE; 1.0 or 5.0 mg/kg, i.p.) or vehicle control was administered to male Sprague-Dawley rats immediately after training in an aversively- or appetitively-motivated task. Aversively-motivated training consisted of a one-trial step-though inhibitory (passive) avoidance task with

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全球贸易项目编号

货号	GTIN
244309-1G	04061826671368