244309
β-咔啉-3-羧酸乙酯
97%
别名:
β-CCE, 9H-吡啶并[3,4-b]吲哚-3-羧酸乙酯
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关于此项目
经验公式（希尔记法）:
C14H12N2O2
化学文摘社编号:
分子量:
240.26
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352100
MDL number:
Assay:
97%
Form:
solid
InChI
1S/C14H12N2O2/c1-2-18-14(17)12-7-10-9-5-3-4-6-11(9)16-13(10)8-15-12/h3-8,16H,2H2,1H3
SMILES string
CCOC(=O)c1cc2c(cn1)[nH]c3ccccc23
InChI key
KOVRZNUMIKACTB-UHFFFAOYSA-N
assay
97%
form
solid
mp
228-230 °C (lit.)
functional group
ester
Gene Information
human ... GABRA1(2554), GABRA2(2555), GABRA3(2556), GABRA5(2558), GABRG2(2566)
rat ... Gabra2(29706)
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
法规信息
新产品
此项目有
S E File et al.
Neuroscience letters, 39(1), 91-94 (1983-08-19)
The effect of CGS 8216 (10 mg/kg) alone and in combination with the imidazodiazepine Ro 15-1788 (10 mg/kg) or ethyl-beta-carboline-3-carboxylate (beta-CCE 1 mg/kg) was tested in the social interaction test of anxiety. All 3 compounds were found to have an
J Auta et al.
The Journal of pharmacology and experimental therapeutics, 280(1), 316-325 (1997-01-01)
A multiple schedule of repeated acquisition and performance of conditional discriminations was used to characterize the effects of two negative allosteric modulators of the gamma-aminobutyric acid (GABAA) receptor (ethyl beta-carboline-3-carboxylate [beta-CCE] and N-methyl-beta-carboline-3-carboxamide [FG-7142]), a hallucinogenic beta-carboline derivative (harmine), a
R Chermat et al.
Pharmacology, biochemistry, and behavior, 56(2), 333-339 (1997-02-01)
The social interaction test was used to examine the effects of an extract of Ginkgo biloba (EGb 761) and its possible interactions with diazepam and ethyl beta-carboline-3-carboxylate (beta-CCE). Pairs of naive (unfamiliar) male Wistar AF rats subjected to the same
P Simon et al.
Pharmacology, biochemistry, and behavior, 45(3), 685-690 (1993-07-01)
We considered the increase in latency for entering into a white-lightened compartment from a black one as an index of anxiety for Swiss albino mice. This has been validated with several reference anxiogenic drugs [pentylenetetrazole, yohimbine, dexamphetamine, and methyl-beta-carboline-3-carboxylate (beta-CCM)].
P J Gatti et al.
Brain research, 693(1-2), 80-87 (1995-09-25)
The purposes of the present study were to: (1) characterize the GABAergic input to vasodepressor neurons in the caudal ventrolateral medulla of the cat, and (2) define more precisely the anatomical localization of these neurons in this species. This was
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