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Merck
CN

253421

3-(2-碘乙酰氨基)-PROXYL

free radical

别名:

3-(2-碘乙酰氨基)-2,2,5,5-四甲基-1-吡咯烷基氧自由基

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关于此项目

经验公式(希尔记法):
C10H18IN2O2
化学文摘社编号:
分子量:
325.17
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352101
MDL number:
Form:
solid
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InChI

1S/C10H18IN2O2/c1-9(2)5-7(12-8(14)6-11)10(3,4)13(9)15/h7H,5-6H2,1-4H3,(H,12,14)

SMILES string

CC1(C)CC(NC(=O)CI)C(C)(C)N1[O]

InChI key

OQIGMSGDHDTSFA-UHFFFAOYSA-N

form

solid

mp

162-164 °C (lit.)

functional group

amide, iodo

storage temp.

2-8°C

Quality Level

General description

3-(2-Iodoacetamido)-PROXYL is a free radical used as a spin probe in spin labeling techniques. This technique is helpful in investigating the dynamic aspects of molecular interactions of substances, proteins, lipids, and cell membranes.

Application

巯基基团特异性自旋标记物。应用包括研究经臭氧处理的人和牛红细胞膜蛋白以及定位肌纤维中的肌球蛋白亚片段。含有硫代磷酸二酯的 DNA 片段可用自旋标记物进行标记。

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Scientific reports, 10(1), 393-393 (2020-01-17)
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Christoph Gmeiner et al.
Physical chemistry chemical physics : PCCP, 19(41), 28360-28380 (2017-10-17)
A combined method, employing NMR and EPR spectroscopies, has demonstrated its strength in solving structures of protein/RNA and other types of biomolecular complexes. This method works particularly well when the large biomolecular complex consists of a limited number of rigid
Site directed nitroxide spin labeling of oligonucleotides for NMR and EPR studies
Shepherd NE, et al.
Tetrahedron, 71(5), 813-819 (2015)
First spin-labeled cytisine derivatives
Polienko YF, et al.
Chemistry of Natural Compounds, 49(2), 311-315 (2013)
Anna I Nalepa et al.
Protein expression and purification, 88(1), 33-40 (2012-12-04)
α(1)-Microglobulin (α(1)m) is a protein of yet unresolved function occurring in blood plasma and urine. It consists of a lipocaline type of fold with two cysteine residues forming a disulfide bridge and the third cysteine-34 remaining a free, somewhat reactive

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