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Merck
CN

27500

柠檬酸三乙酯

greener alternative

≥98.0% (GC)

别名:

柠檬酸乙酯

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关于此项目

线性分子式:
HOC(COOC2H5)(CH2COOC2H5)2
化学文摘社编号:
分子量:
276.28
Beilstein:
1801199
EC 号:
MDL编号:
UNSPSC代码:
12352100
PubChem化学物质编号:
NACRES:
NA.22
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蒸汽密度

9.7 (vs air)

蒸汽压

1 mmHg ( 107 °C)

方案

≥98.0% (GC)

表单

liquid

环保替代产品特性

Less Hazardous Chemical Syntheses
Learn more about the Principles of Green Chemistry.

sustainability

Greener Alternative Product

折射率

n20/D 1.442 (lit.)

沸点

235 °C/150 mmHg (lit.)

密度

1.14 g/mL at 25 °C (lit.)

官能团

ester
hydroxyl

环保替代产品分类

SMILES字符串

CCOC(=O)CC(O)(CC(=O)OCC)C(=O)OCC

InChI

1S/C12H20O7/c1-4-17-9(13)7-12(16,11(15)19-6-3)8-10(14)18-5-2/h16H,4-8H2,1-3H3

InChI key

DOOTYTYQINUNNV-UHFFFAOYSA-N

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一般描述

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柠檬酸三乙酯是一种安全的直接食品添加剂

应用

在对使用近红外(NIR)光谱法测定增塑剂含量和烧结温度对碾压制备型缓释骨架片断裂力的影响进行可行性分析时,柠檬酸三乙酯被用作增塑剂

储存分类代码

10 - Combustible liquids

WGK

WGK 1

闪点(°F)

311.0 °F - closed cup

闪点(°C)

155 °C - closed cup

个人防护装备

Eyeshields, Gloves


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Monice M Fiume et al.
International journal of toxicology, 33(2 suppl), 16S-46S (2014-05-28)
The CIR Expert Panel (Panel) assessed the safety of citric acid, 12 inorganic citrate salts, and 20 alkyl citrate esters as used in cosmetics, concluding that these ingredients are safe in the present practices of use and concentration. Citric acid
Vivek S Dave et al.
Drug development and industrial pharmacy, 41(6), 898-905 (2014-05-03)
The aim of this study was to investigate the feasibility of near-infrared (NIR) spectroscopy for the determination of the influence of sintering temperature and plasticizer levels on the breaking force of extended-release matrix tablets prepared via roller-compaction. Six formulations using
T Quinten et al.
AAPS PharmSciTech, 13(4), 1197-1211 (2012-09-12)
Sustained-release matrix tablets based on Eudragit RL and RS were manufactured by injection moulding. The influence of process temperature; matrix composition; drug load, plasticizer level; and salt form of metoprolol: tartrate (MPT), fumarate (MPF) and succinate (MPS) on ease of
Fang Liu et al.
Journal of controlled release : official journal of the Controlled Release Society, 133(2), 119-124 (2008-10-22)
A novel double-coating enteric system was developed to accelerate drug release in conditions resembling the upper small intestine. The system comprises an inner coat (partially neutralised EUDRAGIT L 30 D-55 and organic acid) and an outer coat (standard EUDRAGIT L
Lisa Claire du Toit et al.
Journal of pharmaceutical sciences, 97(6), 2176-2207 (2007-09-21)
The crux of this research was the pragmatic investigation into the formulation of a reconstitutable multiparticulate anti-tuberculosis drug delivery system for facilitated administration for the attainment of segregated gastrointestinal (GI) delivery of rifampicin (RIF) and isoniazid (INH) in order to

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