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Merck
CN

275158

Sigma-Aldrich

对苯二胺

purified by sublimation, ≥99%

别名:

1,4-二氨基苯, 1,4-苯二胺, 对二氨基苯

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线性分子式:
C6H4(NH2)2
化学文摘社编号:
分子量:
108.14
Beilstein:
742029
EC 号:
MDL编号:
UNSPSC代码:
12352100
PubChem化学物质编号:
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蒸汽密度

3.7 (vs air)

蒸汽压

1.08 mmHg ( 100 °C)

描述

anti-fade reagent

方案

≥99%

纯化方式

sublimation

沸点

267 °C (lit.)

mp

138-143 °C (lit.)

SMILES字符串

Nc1ccc(N)cc1

InChI

1S/C6H8N2/c7-5-1-2-6(8)4-3-5/h1-4H,7-8H2

InChI key

CBCKQZAAMUWICA-UHFFFAOYSA-N

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警示用语:

Danger

危险分类

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Irrit. 2 - Skin Sens. 1 - STOT SE 1 Oral

靶器官

Kidney,Heart,Musculo-skeletal system

储存分类代码

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

闪点(°F)

230.0 °F - closed cup

闪点(°C)

110 °C - closed cup

个人防护装备

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges

法规信息

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分析证书(COA)

Lot/Batch Number

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Jacob Pontoppidan Thyssen et al.
Contact dermatitis, 59(6), 327-343 (2008-12-17)
Many women and men now dye their hair. p-Phenylenediamine (PPD) is a frequent and important component of permanent hair dye products; exposure to it may cause allergic contact sensitization, acute dermatitis, and severe facial oedema. To increase our understanding of
Fabiola Kind et al.
Pediatrics, 131(6), e1974-e1976 (2013-05-22)
Allergic contact dermatitis from nonpermanent black henna tattoos has been frequently reported, particularly in children. Contamination or adulteration of the dyes with para-phenylendiamine has been identified as major cause of active sensitization and elicitation of severe allergic contact dermatitis. Sequelae
Daniel P Poole et al.
American journal of physiology. Gastrointestinal and liver physiology, 309(4), G248-G259 (2015-07-04)
Activated G protein-coupled receptors traffic to endosomes and are sorted to recycling or degradative pathways. Endosomes are also a site of receptor signaling of sustained and pathophysiologically important processes, including inflammation. However, the mechanisms of endosomal sorting of receptors and
Laura M Pot et al.
Contact dermatitis, 68(4), 193-207 (2013-03-21)
Although p-phenylenediamine (PPD) has been recognized as an extreme sensitizer for many years, the exact mechanism of sensitization has not been elucidated yet. Penetration and the ability to bind to proteins are the first two hurdles that an allergen has
Roberta Brambilla et al.
Journal of neuroinflammation, 9, 213-213 (2012-09-12)
Optic neuritis is an acute, demyelinating neuropathy of the optic nerve often representing the first appreciable symptom of multiple sclerosis. Wallerian degeneration of irreversibly damaged optic nerve axons leads to death of retinal ganglion cells, which is the cause of

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