275158
对苯二胺
purified by sublimation, ≥99%
别名:
1,4-二氨基苯, 1,4-苯二胺, 对二氨基苯
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关于此项目
线性分子式:
C6H4(NH2)2
化学文摘社编号:
分子量:
108.14
EC Number:
203-404-7
UNSPSC Code:
12352100
PubChem Substance ID:
Beilstein/REAXYS Number:
742029
MDL number:
InChI key
CBCKQZAAMUWICA-UHFFFAOYSA-N
InChI
1S/C6H8N2/c7-5-1-2-6(8)4-3-5/h1-4H,7-8H2
SMILES string
Nc1ccc(N)cc1
vapor density
3.7 (vs air)
vapor pressure
1.08 mmHg ( 100 °C)
description
anti-fade reagent
assay
≥99%
purified by
sublimation
bp
267 °C (lit.)
mp
138-143 °C (lit.)
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signalword
Danger
Hazard Classifications
Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Irrit. 2 - Skin Sens. 1 - STOT SE 1 Oral
target_organs
Kidney,Heart,Musculo-skeletal system
存储类别
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 3
flash_point_f
230.0 °F - closed cup
flash_point_c
110 °C - closed cup
ppe
Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
法规信息
新产品
此项目有
Jacob Pontoppidan Thyssen et al.
Contact dermatitis, 59(6), 327-343 (2008-12-17)
Many women and men now dye their hair. p-Phenylenediamine (PPD) is a frequent and important component of permanent hair dye products; exposure to it may cause allergic contact sensitization, acute dermatitis, and severe facial oedema. To increase our understanding of
Daniel P Poole et al.
American journal of physiology. Gastrointestinal and liver physiology, 309(4), G248-G259 (2015-07-04)
Activated G protein-coupled receptors traffic to endosomes and are sorted to recycling or degradative pathways. Endosomes are also a site of receptor signaling of sustained and pathophysiologically important processes, including inflammation. However, the mechanisms of endosomal sorting of receptors and
Laura M Pot et al.
Contact dermatitis, 68(4), 193-207 (2013-03-21)
Although p-phenylenediamine (PPD) has been recognized as an extreme sensitizer for many years, the exact mechanism of sensitization has not been elucidated yet. Penetration and the ability to bind to proteins are the first two hurdles that an allergen has
Eva Helaskoski et al.
Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 112(1), 46-52 (2013-12-18)
Oxidative hair dyes commonly contain paraphenylene diamine (PPD) and its derivatives, a well-known cause of delayed hypersensitivity among both consumers and hairdressers. They are also considered possible causes of occupational respiratory diseases. Despite the widespread use of hair dyes, there
Irritant contact dermatitis from a black henna tattoo without sensitization to para-phenylendiamine.
Fabiola Kind et al.
Pediatrics, 131(6), e1974-e1976 (2013-05-22)
Allergic contact dermatitis from nonpermanent black henna tattoos has been frequently reported, particularly in children. Contamination or adulteration of the dyes with para-phenylendiamine has been identified as major cause of active sensitization and elicitation of severe allergic contact dermatitis. Sequelae
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