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Merck
CN

286567

Mephenesin

98%

别名:

3-(2-Methylphenoxy)-1,2-propanediol

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线性分子式:
CH3C6H4OCH2CH(OH)CH2OH
化学文摘社编号:
分子量:
182.22
NACRES:
NA.25
PubChem Substance ID:
UNSPSC Code:
12352202
EC Number:
200-427-4
MDL number:
Assay:
98%
Form:
powder
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InChI key

JWDYCNIAQWPBHD-UHFFFAOYSA-N

InChI

1S/C10H14O3/c1-8-4-2-3-5-10(8)13-7-9(12)6-11/h2-5,9,11-12H,6-7H2,1H3

SMILES string

Cc1ccccc1OCC(O)CO

assay

98%

form

powder

bp

153-154 °C/4 mmHg (lit.)

mp

69-71 °C (lit.)

pictograms

Exclamation mark

signalword

Warning

hcodes

Hazard Classifications

Acute Tox. 4 Oral - Eye Irrit. 2

存储类别

11 - Combustible Solids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

法规信息

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Jing Quan et al.
Bioorganic & medicinal chemistry, 15(4), 1741-1748 (2006-12-21)
A facile, high regioselective enzymatic synthesis approach for the preparation of amphipathic prodrugs with saccharides of mephenesin and chlorphenesin was developed. Firstly, transesterification of two drugs with divinyl dicarboxylates with different carbon chain length was performed under the catalysis of
K Sakitama et al.
Japanese journal of pharmacology, 60(2), 127-131 (1992-10-01)
The effects of morphine-HCl and mephenesin on the flexor reflex mediated by group II afferent fibers were investigated. The flexor reflex was recorded by means of the electromyogram (EMG) evoked in the muscle tibialis anterior by stimulation of the ipsilateral
A Y Junnarkar et al.
Pharmacological research, 26(2), 131-141 (1992-09-01)
The neuropsychopharmacological profile of a new centrally acting skeletal muscle relaxant, 2,4-dihydro[1,2,4]triazolo[3,4-c][1,4]benzothiazine-1-one (IDPH-791), an analogue of triazolobenzothiazine, has been described and compared to mephenesin, a well known centrally-acting muscle relaxant. IDPH-791 was found to be safer and of longer duration
A Schulze-Dirks et al.
Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete, 44(6), 403-406 (1993-06-01)
A case of erythema multiforme-like allergic contact dermatitis due to midysalb, an ointment containing mephenesine is described. Patch testing showed marked sensitization to mephenesine, with positive reactions to different dilutions down to 0.1%. It is unlikely that the weak reaction
Nedim Kasumacic et al.
The Journal of physiology, 588(Pt 24), 4905-4925 (2010-10-22)
Proper control of movement and posture occurs partly via descending projections from the vestibular nuclei to spinal motor circuits. Days before birth in rodents, vestibulospinal neurons develop axonal projections that extend to the spinal cord. How functional these projections are

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