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Merck
CN

291277

丁位十一内酯

98%

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关于此项目

经验公式(希尔记法):
C11H20O2
化学文摘社编号:
分子量:
184.28
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352100
EC Number:
211-915-1
MDL number:
Assay:
98%
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InChI key

YZRXRLLRSPQHDK-UHFFFAOYSA-N

InChI

1S/C11H20O2/c1-2-3-4-5-7-10-8-6-9-11(12)13-10/h10H,2-9H2,1H3

SMILES string

CCCCCCC1CCCC(=O)O1

assay

98%

Gene Information

human ... CYP1A2(1544)

bp

152-155 °C/10.5 mmHg (lit.)

density

0.969 g/mL at 25 °C (lit.)

functional group

ester

General description

Undecanoic δ-lactone has been found to be best substarte for good substrates for lactonase from Sulfolobus islandicus (SisLac).

Application

Undecanoic δ-lactone has been used as substrate to investigate the activities of stimulated and nonstimulated human serum paraoxonase (PON1) samples.

pictograms

Exclamation mark

signalword

Warning

hcodes

Hazard Classifications

Eye Irrit. 2

存储类别

10 - Combustible liquids

wgk

WGK 2

flash_point_f

312.8 °F

flash_point_c

156 °C

ppe

Eyeshields, Gloves, type ABEK (EN14387) respirator filter

法规信息

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分析证书(COA)

Lot/Batch Number

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S Billecke et al.
Drug metabolism and disposition: the biological fate of chemicals, 28(11), 1335-1342 (2000-10-19)
It is well established that human serum paraoxonase (PON1) catalyzes the hydrolysis of organophosphate insecticides and nerve agents, as well as that of a number of aromatic carboxylic acid esters. Our laboratory has recently found a new class of PON1
Julien Hiblot et al.
PloS one, 7(10), e47028-e47028 (2012-10-17)
A new member of the Phosphotriesterase-Like Lactonases (PLL) family from the hyperthermophilic archeon Sulfolobus islandicus (SisLac) has been characterized. SisLac is a native lactonase that exhibits a high promiscuous phosphotriesterase activity. SisLac thus represents a promising target for engineering studies

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