292648
Dihydrofluorescein diacetate
97%
别名:
Diacetyldihydrofluorescein
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关于此项目
经验公式（希尔记法）:
C24H18O7
化学文摘社编号:
分子量:
418.40
UNSPSC Code:
12171500
NACRES:
NA.47
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
364167
InChI
1S/C24H18O7/c1-13(25)29-15-7-9-19-21(11-15)31-22-12-16(30-14(2)26)8-10-20(22)23(19)17-5-3-4-6-18(17)24(27)28/h3-12,23H,1-2H3,(H,27,28)
SMILES string
CC(=O)Oc1ccc2C(c3ccc(OC(C)=O)cc3Oc2c1)c4ccccc4C(O)=O
InChI key
YKSJJXGQHSESKB-UHFFFAOYSA-N
assay
97%
mp
213-215 °C (lit.)
solubility
acetone: 50 mg/mL
fluorescence
λex 272 nm in methanol, λex 490; λem 514 (Reaction product)
application(s)
diagnostic assay manufacturing
hematology
histology
storage temp.
room temp
General description
Dihydrofluorescein diacetate (H2FDA) is an esterified derivative of dihydrofluorescein. H2FDA is one of the widely used fluorescent probes employed in the intracellular reactive oxygen species (ROS) detection.
存储类别
13 - Non Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Floriane L'Haridon et al.
PLoS pathogens, 7(7), e1002148-e1002148 (2011-08-11)
Wounded leaves of Arabidopsis thaliana show transient immunity to Botrytis cinerea, the causal agent of grey mould. Using a fluorescent probe, histological staining and a luminol assay, we now show that reactive oxygen species (ROS), including H(2)O(2) and O(2) (-)
Matthieu Dallons et al.
Frontiers in pharmacology, 11, 79-79 (2020-03-11)
Doxorubicin (DOX) is an anticancer drug widely used in oncology. The main limitation to DOX treatments though is due to the cumulative dose that may lead to cardiotoxicity. Clinically, DOX-induced cardiomyopathy develops as a progressive heart failure consecutive to a
Abhishek K Verma et al.
Frontiers in microbiology, 9, 1489-1489 (2018-07-24)
Chandipura Virus (CHPV) a negative-stranded RNA virus belonging to the Rhabdoviridae family, has been previously reported to bring about neuronal apoptosis by stimulating oxidative stress. Our in silico data suggested the involvement of Angiotensin II in intracellular Ca2+ secretion within
Emna Beneloujaephajri et al.
BMC plant biology, 13, 160-160 (2013-10-19)
Wounded leaves of Arabidopsis thaliana produce reactive oxygen species (ROS) within minutes after wounding and become resistant to the pathogenic fungus Botrytis cinerea at a local level. This fast response of the plants to the wound is called wound-induced resistance
Gessica Sousa et al.
Scientific reports, 9(1), 670-670 (2019-01-27)
The termite gut is an efficient decomposer of polyphenol-rich diets, such as lignocellulosic biomasses, and it has been proposed that non-enzymatic oxidative mechanisms could be involved with the digestive process in these animals. However, oxidant levels are completely unknown in
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