292648
Dihydrofluorescein diacetate
97%
别名:
Diacetyldihydrofluorescein
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关于此项目
经验公式（希尔记法）:
C24H18O7
化学文摘社编号:
分子量:
418.40
UNSPSC Code:
12171500
NACRES:
NA.47
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
364167
InChI
1S/C24H18O7/c1-13(25)29-15-7-9-19-21(11-15)31-22-12-16(30-14(2)26)8-10-20(22)23(19)17-5-3-4-6-18(17)24(27)28/h3-12,23H,1-2H3,(H,27,28)
SMILES string
CC(=O)Oc1ccc2C(c3ccc(OC(C)=O)cc3Oc2c1)c4ccccc4C(O)=O
InChI key
YKSJJXGQHSESKB-UHFFFAOYSA-N
assay
97%
mp
213-215 °C (lit.)
solubility
acetone: 50 mg/mL
fluorescence
λex 272 nm in methanol, λex 490; λem 514 (Reaction product)
application(s)
diagnostic assay manufacturing
hematology
histology
storage temp.
room temp
General description
Dihydrofluorescein diacetate (H2FDA) is an esterified derivative of dihydrofluorescein. H2FDA is one of the widely used fluorescent probes employed in the intracellular reactive oxygen species (ROS) detection.
存储类别
13 - Non Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Emna Beneloujaephajri et al.
BMC plant biology, 13, 160-160 (2013-10-19)
Wounded leaves of Arabidopsis thaliana produce reactive oxygen species (ROS) within minutes after wounding and become resistant to the pathogenic fungus Botrytis cinerea at a local level. This fast response of the plants to the wound is called wound-induced resistance
Alexandra Vaccaro et al.
PLoS genetics, 8(7), e1002806-e1002806 (2012-07-14)
TDP-43 is a multifunctional nucleic acid binding protein linked to several neurodegenerative diseases including Amyotrophic Lateral Sclerosis (ALS) and Frontotemporal Dementia. To learn more about the normal biological and abnormal pathological role of this protein, we turned to Caenorhabditis elegans
Toshiyuki Matsunaga et al.
Anti-cancer drugs, 25(8), 868-877 (2014-04-20)
Continuous exposure to daunorubicin (DNR) confers resistance against the drug-elicited lethality of leukemic cells and then reduces the remission rate. However, the detailed mechanisms involved in resistance development of leukemic cells to DNR remain unclear. Upregulation of aldo-keto reductases (AKRs)
Gessica Sousa et al.
Scientific reports, 9(1), 670-670 (2019-01-27)
The termite gut is an efficient decomposer of polyphenol-rich diets, such as lignocellulosic biomasses, and it has been proposed that non-enzymatic oxidative mechanisms could be involved with the digestive process in these animals. However, oxidant levels are completely unknown in
Chandan K. Sen, Lester Packer
Redox Cell Biology and Genetics, (2002)
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