300683
α-1,2,3,4,5,6-六氯环己烷
99%
别名:
α-BHC
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关于此项目
经验公式（希尔记法）:
C6H6Cl6
化学文摘社编号:
分子量:
290.83
EC Number:
206-270-8
UNSPSC Code:
12352100
PubChem Substance ID:
Beilstein/REAXYS Number:
7073451
MDL number:
InChI key
JLYXXMFPNIAWKQ-SHFUYGGZSA-N
InChI
1S/C6H6Cl6/c7-1-2(8)4(10)6(12)5(11)3(1)9/h1-6H/t1-,2-,3-,4-,5+,6+/m1/s1
SMILES string
Cl[C@@H]1[C@H](Cl)[C@@H](Cl)[C@H](Cl)[C@@H](Cl)[C@H]1Cl
assay
99%
form
solid
mp
156-161 °C (lit.)
General description
α-1,2,3,4,5,6-Hexachlorocyclohexane is a racemic compound with anticonvulsant and tremorogenic activities and its accumulation in cerebral white over grey matter in rats was confirmed. Administration of α -1,2,3,4,5,6-hexachlorocyclohexane (α-HCH) to rats decreased the utilization of [2-14C]orotic acid for the synthesis of liver cytidine nucleotides.
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 3 Oral - Acute Tox. 4 Dermal - Aquatic Acute 1 - Aquatic Chronic 1 - Carc. 2
存储类别
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges
法规信息
监管及禁止进口产品
此项目有
J Seifert et al.
Toxicology, 7(2), 155-161 (1977-04-01)
Administration of alpha-1,2,3,4,5,6-hexachlorocyclohexane (alpha-HCH) to rats decreased the utilization of [2-14C]orotic acid for the synthesis of liver cytidine nucleotides. The specific radioactivities of uridine components of the acid-soluble pool and rRNA increased during the first hours of treatment with the
J Portig et al.
Xenobiotica; the fate of foreign compounds in biological systems, 19(1), 123-130 (1989-01-01)
1. Whole-body autoradiographic evidence that alpha-1,2,3,4,5,6-hexachlorocyclohexane (alpha-HCH), a racemic compound with anticonvulsant and tremorogenic activities, accumulates in cerebral white over grey matter was confirmed in rats using unlabelled compound and g.l.c. determination in tissue samples. 2. Accumulation in, and retention
Sung-Deuk Choi et al.
Environmental science & technology, 45(20), 8834-8841 (2011-09-13)
An understanding of the factors that control the time trends of persistent organic pollutants (POPs) in the environment is required to evaluate the effectiveness of emission reductions and to predict future exposure. Using a regional contaminant fate model, CoZMo-POP 2
Pernilla Carlsson et al.
Journal of environmental monitoring : JEM, 14(5), 1437-1443 (2012-04-07)
A pilot study is presented evaluating selected chlorinated pesticides as chemical tracers for water masses in a sub-Arctic fjord system (Godthåbsfjord, western Greenland). Polyoxymethylene (POM) based passive water samplers were deployed during summer-autumn 2010. The levels of the analysed chlorinated
M Pućko et al.
Environmental science & technology, 46(21), 11862-11869 (2012-10-09)
During the summer of 2009, we sampled 14 partially refrozen melt ponds and the top 1 m of old ice in the pond vicinity for α-hexachlorocyclohexane (α-HCH) concentrations and enantiomer fractions (EFs) in the Beaufort Sea. α-HCH concentrations were 3
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