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Merck
CN

302023

(−)-2-Oxo-4-thiazolidinecarboxylic acid

97%

别名:

(R)-(−)-2-Oxothiazolidine-4-carboxylic acid, L-(−)-2-Oxothiazolidine-4-carboxylic acid

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关于此项目

经验公式（希尔记法）:
C4H5NO3S
化学文摘社编号:
19771-63-2
分子量:
147.15
PubChem Substance ID:
24858227
UNSPSC Code:
12352200
MDL number:
MFCD00066092
Beilstein/REAXYS Number:
4179169

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SMILES string

OC(=O)[C@@H]1CSC(=O)N1

assay

97%

optical activity

[α]19/D −60°, c = 1 in H2O

mp

174 °C (dec.) (lit.)

Application

An intermediate in the total synthesis of (+)-latrunculin A.

存储类别

11 - Combustible Solids

wgk

WGK 3

ppe

dust mask type N95 (US), Eyeshields, Gloves

法规信息

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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
02830AE
12529TD
12408CY
12215CQ
11418TB

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The Journal of Organic Chemistry, 57, 5292-5292 (1992)
Michael P Gamcsik et al.
Neurochemical research, 36(3), 443-451 (2010-12-17)
The cysteine precursor L-2-oxothiazolidine-4-carboxylate (OTZ, procysteine) can raise cysteine concentration, and thus glutathione levels, in some tissues. OTZ has therefore been proposed as a prodrug for combating oxidative stress. We have synthesized stable isotope labeled OTZ (i.e. L-2-oxo-[5-(13)C]-thiazolidine-4-carboxylate, (13)C-OTZ) and
M J Clemente-Moreno et al.
Plant biology (Stuttgart, Germany), 12(1), 88-97 (2010-07-27)
The effect of treatment with benzothiadiazole (BTH) or l-2-oxothiazolidine-4-carboxylic acid (OTC), and their interaction with Plum pox virus (PPV) infection, on antioxidative metabolism of pea plants was studied at the subcellular level. PPV infection produced a 20% reduction in plant
Xian Fan et al.
Alcoholism, clinical and experimental research, 35(10), 1866-1875 (2011-05-17)
Alcohol abuse and HIV-1 infection frequently coexist, and these individuals are at high risk for serious lung infections and respiratory failure. Although alcohol ingestion and HIV-1 transgene expression have been shown to independently cause oxidative stress and disrupt alveolar epithelial
Nghi Phung et al.
International journal of molecular medicine, 24(2), 171-180 (2009-07-07)
The mechanistic significance of oxidative stress to fibrogenesis in the methionine and choline-deficient (MCD) diet-induced model of steatohepatitis was evaluated by antioxidant intervention, using either vitamin E or L-2-oxothiazolidine-4-carboxylate (OTC), a cysteine precursor that promotes glutathione synthesis. Significant depletion of
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