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Merck
CN

306797

Sigma-Aldrich

(S)-(-)-2-氯丙酸

99%

别名:

(S)-(-)-2-Chloropropanoic acid, L-α-氯丙酸

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关于此项目

线性分子式:
CH3CH(Cl)CO2H
化学文摘社编号:
分子量:
108.52
Beilstein:
1720257
EC 号:
MDL编号:
UNSPSC代码:
12352101
PubChem化学物质编号:
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方案

99%

表单

liquid

旋光性

[α]25/D −14°, neat

折射率

n20/D 1.4347 (lit.)

沸点

77 °C/10 mmHg (lit.)

密度

1.249 g/mL at 25 °C (lit.)

SMILES字符串

C[C@H](Cl)C(O)=O

InChI

1S/C3H5ClO2/c1-2(4)3(5)6/h2H,1H3,(H,5,6)/t2-/m0/s1

InChI key

GAWAYYRQGQZKCR-REOHCLBHSA-N

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应用

(S)-(-)-2-氯丙酸可用于制备(S)-(-)-2-氯丙酰氯 和 DOTMA ([αR*(αR*,α′R*,α”R*,α”′R*)]-(α,α′,α”,α”′)-四甲基-1,4,7,10-四氮杂环十二烷-1,4,7,10-四乙酸)配体。

警示用语:

Danger

危险分类

Acute Tox. 4 Dermal - Acute Tox. 4 Oral - Eye Dam. 1 - Skin Corr. 1A - STOT RE 2

储存分类代码

8A - Combustible corrosive hazardous materials

WGK

WGK 1

闪点(°F)

222.8 °F - closed cup

闪点(°C)

106 °C - closed cup

个人防护装备

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter

法规信息

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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Synthesis of optically pure. alpha.-alkylated. alpha.-amino acids and a single-step method for enantiomeric excess determination.
Kruizinga WH, et al.
The Journal of Organic Chemistry, 53(8) (1988)
A new ytterbium chelate as contrast agent in chemical shift imaging and temperature sensitive probe for MR spectroscopy.
Aime S, et al.
Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine, 35(5), 648-651 (1996)
Fanny Mochel et al.
Molecular genetics and metabolism, 84(4), 305-312 (2005-03-23)
A six-day-old girl was referred for severe hepatic failure, dehydratation, axial hypotonia, and both lactic acidosis and ketoacidosis. Biotin-unresponsive pyruvate carboxylase deficiency type B was diagnosed. Triheptanoin, an odd-carbon triglyceride, was administrated as a source for acetyl-CoA and anaplerotic propionyl-CoA.
Atsushi Kurata et al.
The Journal of biological chemistry, 280(21), 20286-20291 (2005-03-23)
A soil bacterium, Burkholderia sp. WS, grows on 2-chloroacrylate as the sole carbon source. To identify the enzymes metabolizing 2-chloroacrylate, we carried out comparative two-dimensional gel electrophoresis of the proteins from 2-chloroacrylate- and lactate-grown bacterial cells. As a result, we
Stephen Duffell et al.
Neurotoxicology, 25(6), 1031-1040 (2004-10-12)
Previous studies have shown that L-2-chloropropionic acid (L-CPA) produces necrosis to cerebellar granule cells with some associated Purkinje cell damage in the rat. We have re-evaluated the neuropathology using the original sections and fresh sections from archived brain material from

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