SMILES string
OC(=O)CC1c2ccccc2-c3ccccc13
InChI
1S/C15H12O2/c16-15(17)9-14-12-7-3-1-5-10(12)11-6-2-4-8-13(11)14/h1-8,14H,9H2,(H,16,17)
InChI key
WFSMJMTYIMFHPV-UHFFFAOYSA-N
assay
99%
mp
133-135 °C (lit.)
Gene Information
rat ... Akr1b1(24192)
Application
9-Fluoreneacetic acid was used in preparation of pyrokinin class of insect neuropeptides. It was also used in preparation of N-(9-fluoreneacetyl)-L-leucine.
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Isaac O Donkor et al.
Journal of medicinal chemistry, 51(14), 4346-4350 (2008-07-19)
A series of peptidyl alpha-ketoacids and alpha-ketoesters was synthesized and studied as mu-calpain inhibitors. Docking studies revealed that the mu-calpain inhibitory activity of the compounds is influenced by hydrogen bonding interactions and the potential for ionic interaction with active site
A J Bourque et al.
Biomedical chromatography : BMC, 8(2), 53-62 (1994-03-01)
An automated system is described for the simultaneous extraction and derivatization of nucleophilic compounds from various biological media. The method includes the use of a solid-phase reagent containing a 9-fluorenylacetate activated ester. The reagent is based on a controlled pore
F X Zhou et al.
Journal of chromatography, 619(1), 93-101 (1993-09-08)
A simple, highly sensitive and selective method is described for adamantanamine determination in plasma and urine by high-performance liquid chromatography with fluorescence detection. The method involved a simultaneous extraction and derivatization of biological fluids with a 9-fluoreneacetate (9-FA) solid-phase derivatization
H M Zhang et al.
Journal of pharmaceutical and biomedical analysis, 10(8), 577-586 (1992-08-01)
Two silica reagents based on a 4-hydroxy-3-nitrobenzoyl backbone were synthesized and characterized with 9-fluorenylmethoxycarbonyl (FMOC) and 9-fluoreneacetyl (FA) tags. These reagents were tested by derivatization of primary and secondary amines. Derivatization conditions such as temperature, time and triethylamine catalyst were
Y S Lee et al.
Bioorganic & medicinal chemistry, 6(10), 1811-1819 (1998-12-05)
Molecular modeling studies using the CHARMM method have been conducted to study the binding modes of aldose reductase inhibitors at the active site of aldose reductase. The energy minimized structures of aldose reductase with six structurally diverse inhibitors (spirofluorene-9,5'-imidazolidine-2',4'-dione (1)
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