InChI
1S/C5H6N2O3/c1-3-5(7(8)9)4(2)10-6-3/h1-2H3
SMILES string
Cc1noc(C)c1[N+]([O-])=O
InChI key
PMQFLWLYAXYFHG-UHFFFAOYSA-N
assay
98%
mp
67-69 °C (lit.)
functional group
nitro
Application
3,5-Dimethyl-4-nitroisoxazole was used in the synthesis of:
- series of methylene bis-isoxazolo[4,5-b]azepines, via reaction with methylene bis-chalcones
- phenylmethylene bis-isoxazolo[4,5-b]azepine derivatives
- 3-arylglutaric acids, bis-isoxazoles and bis-pyrazoles
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
法规信息
新产品
此项目有
E Rajanarendar et al.
Bioorganic & medicinal chemistry letters, 22(1), 149-153 (2011-12-14)
A series of novel phenylmethylene bis-isoxazolo[4,5-b]azepine derivatives (10) have been synthesized from 3-methyl-4-nitro-5-styrylisoxazoles 6. The reaction of 6 with 3,5-dimethyl-4-nitroisoxazole (7) in piperidine afforded the Michael type adducts 8, which on treatment with different substituted chalcones in the presence of
Three multicomponent reactions of 3, 5-dimethyl-4-nitroisoxazole.
Adamo MFA, et al.
Tetrahedron, 63(39), 9741-9745 (2007)
E Rajanarendar et al.
European journal of medicinal chemistry, 50, 344-349 (2012-03-06)
A series of novel methylene bis-isoxazolo[4,5-b]azepines have been synthesized by reaction of 3,5-dimethyl-4-nitroisoxazole 6 with an appropriate methylene bis-chalcones 7 to obtain various Michael adducts 8a-i, which on treatment with SnCl(2)-MeOH underwent reductive cyclization to afford the title compounds 9a-i.
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系客户支持