340383
1-氨基-1-脱氧-D-山梨醇
98%
别名:
1-氨基-1-脱氧山梨醇, D-葡糖胺
方案
98%
旋光性
[α]20/D −7.0°, neat
自燃温度
~734 °F
mp
127 °C (dec.) (lit.)
SMILES字符串
NC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO
InChI
1S/C6H15NO5/c7-1-3(9)5(11)6(12)4(10)2-8/h3-6,8-12H,1-2,7H2/t3-,4+,5+,6+/m0/s1
InChI key
SDOFMBGMRVAJNF-SLPGGIOYSA-N
法规信息
新产品
此项目有
Qi Qin et al.
CNS neuroscience & therapeutics, 23(2), 162-173 (2016-12-13)
Mutations in leucine-rich repeat kinase 2 (LRRK2) are the most prevalent cause of familial and sporadic Parkinson's disease (PD). Because most pathogenic LRRK2 mutations result in enhanced kinase activity, it suggests that LRRK2 inhibitors may serve as a potential treatment
Ryuto Hara et al.
Neuroscience letters, 728, 134958-134958 (2020-04-13)
We recently showed that the mesolimbic dopaminergic system was tonically suppressed during chronic pain by enhanced corticotropin releasing factor (CRF) signaling within the dorsolateral bed nucleus of the stria terminalis (dlBNST), and that inhibition of intra-dlBNST CRF signaling restored the
Karima Ait Ouares et al.
The European journal of neuroscience, 49(1), 6-26 (2018-11-06)
Optogenetics is based on the selective expression of exogenous opsins by neurons allowing experimental control of their electrical activity using visible light. The interpretation of the results of optogenetic experiments is based on the assumption that light stimulation selectively acts
Iurii Semenov et al.
Bioelectrochemistry (Amsterdam, Netherlands), 105, 65-71 (2015-05-27)
We tested if picosecond electric pulses (psEP; 190 kV/cm, 500 ps at 50% height), which are much shorter than channel activation time, can activate voltage-gated (VG) channels. Cytosolic Ca(2+) was monitored by Fura-2 ratiometric imaging in GH3 and NG108 cells
A F Garcia et al.
Psychopharmacology, 237(10), 2929-2941 (2020-06-20)
Drug addiction is a chronic disease defined by a complex set of characteristics, including loss of control over drug intake and persistent drug craving, which primarily affects a small percentage of people who try drugs. Although many models have been
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