340383
1-氨基-1-脱氧-D-山梨醇
98%
别名:
1-氨基-1-脱氧山梨醇, D-葡糖胺
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关于此项目
经验公式（希尔记法）:
C6H15NO5
化学文摘社编号:
分子量:
181.19
EC Number:
207-677-3
UNSPSC Code:
12352200
PubChem Substance ID:
Beilstein/REAXYS Number:
1721895
MDL number:
InChI key
SDOFMBGMRVAJNF-SLPGGIOYSA-N
InChI
1S/C6H15NO5/c7-1-3(9)5(11)6(12)4(10)2-8/h3-6,8-12H,1-2,7H2/t3-,4+,5+,6+/m0/s1
SMILES string
NC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO
assay
98%
optical activity
[α]20/D −7.0°, neat
autoignition temp.
~734 °F
mp
127 °C (dec.) (lit.)
法规信息
新产品
此项目有
Qi Qin et al.
CNS neuroscience & therapeutics, 23(2), 162-173 (2016-12-13)
Mutations in leucine-rich repeat kinase 2 (LRRK2) are the most prevalent cause of familial and sporadic Parkinson's disease (PD). Because most pathogenic LRRK2 mutations result in enhanced kinase activity, it suggests that LRRK2 inhibitors may serve as a potential treatment
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We recently showed that the mesolimbic dopaminergic system was tonically suppressed during chronic pain by enhanced corticotropin releasing factor (CRF) signaling within the dorsolateral bed nucleus of the stria terminalis (dlBNST), and that inhibition of intra-dlBNST CRF signaling restored the
Iurii Semenov et al.
Bioelectrochemistry (Amsterdam, Netherlands), 105, 65-71 (2015-05-27)
We tested if picosecond electric pulses (psEP; 190 kV/cm, 500 ps at 50% height), which are much shorter than channel activation time, can activate voltage-gated (VG) channels. Cytosolic Ca(2+) was monitored by Fura-2 ratiometric imaging in GH3 and NG108 cells
Karima Ait Ouares et al.
The European journal of neuroscience, 49(1), 6-26 (2018-11-06)
Optogenetics is based on the selective expression of exogenous opsins by neurons allowing experimental control of their electrical activity using visible light. The interpretation of the results of optogenetic experiments is based on the assumption that light stimulation selectively acts
William D Hendricks et al.
Proceedings of the National Academy of Sciences of the United States of America, 116(22), 10994-10999 (2019-05-16)
In temporal lobe epilepsy, sprouting of hippocampal mossy fiber axons onto dentate granule cell dendrites creates a recurrent excitatory network. However, unlike mossy fibers projecting to CA3, sprouted mossy fiber synapses depress upon repetitive activation. Thus, despite their proximal location
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