346403
3-(1H-四唑-5-基)-9H-硫代呫吨-9-酮-10,10-二氧化物 一水合物
95%
别名:
四唑硫蒽酮
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关于此项目
经验公式（希尔记法）:
C14H8N4O3S · H2O
化学文摘社编号:
分子量:
330.32
UNSPSC Code:
12352100
PubChem Substance ID:
EC Number:
257-397-0
MDL number:
InChI key
YRXFSKFCFQRWHG-UHFFFAOYSA-N
InChI
1S/C14H8N4O3S.H2O/c19-13-9-3-1-2-4-11(9)22(20,21)12-7-8(5-6-10(12)13)14-15-17-18-16-14;/h1-7H,(H,15,16,17,18);1H2
SMILES string
[H]O[H].O=C1c2ccccc2S(=O)(=O)c3cc(ccc13)-c4nnn[nH]4
assay
95%
mp
255 °C (dec.) (lit.)
法规信息
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John P Russell et al.
The Journal of pharmacology and experimental therapeutics, 368(2), 299-307 (2018-11-11)
Abdominal pain represents a significant complaint in patients with irritable bowel syndrome (IBS). While the etiology of IBS is incompletely understood, prior exposure to gastrointestinal inflammation or psychologic stress is frequently associated with the development of symptoms. Inflammation or stress-induced
B Xue et al.
Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society, 27(4), 550-558 (2015-03-31)
Endotoxin exposure may be followed by visceral hypersensitvity but potential mechanisms are not fully explored. We aimed to test the hypothesis that mast cells and the cyclooxygenase pathway (COX) mediate modulation of afferent nerve sensitivity following systemic endotoxin. C57Bl6 mice
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