359785
硫喔星 盐酸盐
97%
别名:
8-巯基喹啉 盐酸盐, 喹啉-8-硫醇 盐酸盐
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关于此项目
经验公式（希尔记法）:
C9H7NS · HCl
化学文摘社编号:
分子量:
197.68
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
251-785-3
Beilstein/REAXYS Number:
3694939
MDL number:
Assay:
97%
Form:
solid
InChI key
RWBSBQAUAJSGHY-UHFFFAOYSA-N
InChI
1S/C9H7NS.ClH/c11-8-5-1-3-7-4-2-6-10-9(7)8;/h1-6,11H;1H
SMILES string
Cl[H].Sc1cccc2cccnc12
assay
97%
form
solid
mp
165 °C (dec.) (lit.)
solubility
ethanol: soluble 50 mg/mL, clear, dark orange-brown
Application
8-Quinolinethiol hydrochloride may be used in the synthesis of N2S2-donor tetradentate ligands.
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
法规信息
新产品
此项目有
N Ashizawa et al.
Biological & pharmaceutical bulletin, 17(2), 212-216 (1994-02-01)
The effects of metal chelators on endothelin (ET)-converting enzyme (ECE) activity in vivo were examined. Three compounds, (2,3-dimercapto-1-propanol (DMP), toluene-3,4-dithiol (TDT) and 8-mercaptoquinoline (8-MQ)), which inhibited ECE in in vitro studies, exhibited inhibitory activity towards big ET-1-induced sudden death in
Synthesis and coordination chemistry of tetradentate ligands containing two bidentate thioquinoline units: mononuclear complexes with Cu (I) and Cu (II), and a coordination polymer with Cu (I).
Tavacoli S, et al.
Polyhedron, 22(4), 507-514 (2003)
N Ashizawa et al.
Biological & pharmaceutical bulletin, 17(2), 207-211 (1994-02-01)
The effects of various metal chelators on endothelin (ET)-converting enzyme (ECE) activity were examined in vitro. Three chelators, 2,3-dimercapto-1-propanol (DMP), toluene-3,4-dithiol (TDT) and 8-mercaptoquinoline (8-MQ), were found to dose-dependently inhibit ECE activity, but this inhibition was much weaker compared with
W D Figg et al.
Journal of chromatography, 652(2), 187-194 (1994-02-11)
This paper describes a reversed-phase, high-performance liquid chromatographic (HPLC) method for the isolation, detection, and quantification of TNP-470 (I) and one of its active metabolites, AGM-1883 (II), from plasma. These compounds are initially extracted from plasma with an organic solvent
K Borg-Neczak et al.
Pharmacology & toxicology, 74(3), 185-192 (1994-03-01)
Oral administration of Ni2+ together with 8-hydroxyquinoline (8-OH-quinoline), 8-mercaptoquinoline (8-SH-quinoline) or 5-chloro-7-iodo-8-hydroxyquinoline (clioquinol) resulted in increased tissue levels of the metal in several tissues of mice in comparison with animals given the Ni2+ alone. Ni2+ forms lipophilic complexes with these
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