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Merck
CN

361518

1-羟基芘

98%

别名:

1-Pyrenol

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关于此项目

经验公式(希尔记法):
C16H10O
化学文摘社编号:
分子量:
218.25
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352100
MDL number:
Assay:
98%
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assay

98%

mp

179-182 °C (lit.)

SMILES string

Oc1ccc2ccc3cccc4ccc1c2c34

InChI

1S/C16H10O/c17-14-9-7-12-5-4-10-2-1-3-11-6-8-13(14)16(12)15(10)11/h1-9,17H

InChI key

BIJNHUAPTJVVNQ-UHFFFAOYSA-N

General description

1-羟基芘作为尿液代谢产物,是多环芳烃 (PAH) 暴露的标志物。1-羟基芘是暴露于芘的重要生物标志物。

Application

1-羟基芘适用于以下研究:
  • 探讨用简单的荧光法快速检测和定量测定暴露于沉积物相关芘的杂色沙蚕组织提取液中的 1-羟基芘。
  • 探讨细胞色素 P450 1A1 (CYP1A1) 和 2E1 (CYP2E1) 以及谷胱甘肽 S-转移酶 mu (GSTM1) 和 θ (GSTT1) 的基因多态性对飞机维修工人尿 1-羟基芘和 2-萘酚水平的影响。
  • 研究爱沙尼亚油页岩加工厂焦化厂工人的多环芳烃暴露情况。


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存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves



历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Jena Webb et al.
International archives of occupational and environmental health, 91(1), 105-115 (2017-09-25)
Polycyclic aromatic hydrocarbons (PAHs) are contaminants with carcinogenic effects but little is known about their presence in environments surrounding oil drilling operations and spills or exposure levels in nearby communities. The objective of this study was to characterize PAH levels
Hueiwang Anna Jeng et al.
Journal of hazardous materials, 244-245, 436-443 (2013-01-15)
The objective of the cross-sectional study was to assess whether exposure to polycyclic aromatic hydrocarbons (PAHs) from coke oven emissions contributed to alteration of semen quality and sperm DNA integrity in nonsmoking workers. Nonsmoking coke oven workers from a steel
Zheng Li et al.
Chemical research in toxicology, 25(7), 1452-1461 (2012-06-06)
Human exposure to polycyclic aromatic hydrocarbons (PAHs) can be assessed by biomonitoring of their urinary monohydroxylated metabolites (OH-PAHs). Limited information exists on the human pharmacokinetics of OH-PAHs. This study aimed to investigate the excretion half-life of 1-hydroxypyrene (1-PYR), the most



全球贸易项目编号

货号GTIN
361518-100MG04061831824278
361518-500MG04061831824285