质量水平
方案
98%
mp
179-182 °C (lit.)
SMILES字符串
Oc1ccc2ccc3cccc4ccc1c2c34
InChI
1S/C16H10O/c17-14-9-7-12-5-4-10-2-1-3-11-6-8-13(14)16(12)15(10)11/h1-9,17H
InChI key
BIJNHUAPTJVVNQ-UHFFFAOYSA-N
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一般描述
1-羟基芘作为尿液代谢产物，是多环芳烃 (PAH) 暴露的标志物。1-羟基芘是暴露于芘的重要生物标志物。
应用
1-羟基芘适用于以下研究：
- 探讨用简单的荧光法快速检测和定量测定暴露于沉积物相关芘的杂色沙蚕组织提取液中的 1-羟基芘。
- 探讨细胞色素 P450 1A1 (CYP1A1) 和 2E1 (CYP2E1) 以及谷胱甘肽 S-转移酶 mu (GSTM1) 和 θ (GSTT1) 的基因多态性对飞机维修工人尿 1-羟基芘和 2-萘酚水平的影响。
- 研究爱沙尼亚油页岩加工厂焦化厂工人的多环芳烃暴露情况。
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
dust mask type N95 (US), Eyeshields, Gloves
Jena Webb et al.
International archives of occupational and environmental health, 91(1), 105-115 (2017-09-25)
Polycyclic aromatic hydrocarbons (PAHs) are contaminants with carcinogenic effects but little is known about their presence in environments surrounding oil drilling operations and spills or exposure levels in nearby communities. The objective of this study was to characterize PAH levels
Hueiwang Anna Jeng et al.
Journal of hazardous materials, 244-245, 436-443 (2013-01-15)
The objective of the cross-sectional study was to assess whether exposure to polycyclic aromatic hydrocarbons (PAHs) from coke oven emissions contributed to alteration of semen quality and sperm DNA integrity in nonsmoking workers. Nonsmoking coke oven workers from a steel
Christiana A Demetriou et al.
Occupational and environmental medicine, 69(9), 619-627 (2012-07-10)
The association between ambient air pollution exposure and lung cancer risk has been investigated in prospective studies and the results are generally consistent, indicating that long-term exposure to air pollution may cause lung cancer. Despite the prospective nature and consistent
Gabriela Domínguez-Cortinas et al.
Environmental science and pollution research international, 20(1), 351-357 (2012-05-01)
In developing countries, the management of environmental toxicants is inadequate, thus, humans may be exposed to levels higher than normal levels (background levels). Therefore, the aim of this study was to evaluate the exposure level of Mexican children to dichlorodiphenyltrichloroethane
Anders M B Giessing et al.
Marine environmental research, 56(5), 599-615 (2003-08-21)
The uptake of polycyclic aromatic hydrocarbons (PAHs) by marine deposit-feeding invertebrates can be determined by screening for PAH-derived metabolites. We identified 1-hydroxypyrene as the only intermediate metabolite in tissue of four species of deposit-feeding polychaetes, Nereis diversicolor, Nereis virens, Arenicola
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