产品名称
1-羟基芘, 98%
InChI
1S/C16H10O/c17-14-9-7-12-5-4-10-2-1-3-11-6-8-13(14)16(12)15(10)11/h1-9,17H
SMILES string
Oc1ccc2ccc3cccc4ccc1c2c34
InChI key
BIJNHUAPTJVVNQ-UHFFFAOYSA-N
assay
98%
mp
179-182 °C (lit.)
Quality Level
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Application
1-羟基芘适用于以下研究：
- 探讨用简单的荧光法快速检测和定量测定暴露于沉积物相关芘的杂色沙蚕组织提取液中的 1-羟基芘。
- 探讨细胞色素 P450 1A1 (CYP1A1) 和 2E1 (CYP2E1) 以及谷胱甘肽 S-转移酶 mu (GSTM1) 和 θ (GSTT1) 的基因多态性对飞机维修工人尿 1-羟基芘和 2-萘酚水平的影响。
- 研究爱沙尼亚油页岩加工厂焦化厂工人的多环芳烃暴露情况。
General description
1-羟基芘作为尿液代谢产物，是多环芳烃 (PAH) 暴露的标志物。1-羟基芘是暴露于芘的重要生物标志物。
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
Zheng Li et al.
Chemical research in toxicology, 25(7), 1452-1461 (2012-06-06)
Human exposure to polycyclic aromatic hydrocarbons (PAHs) can be assessed by biomonitoring of their urinary monohydroxylated metabolites (OH-PAHs). Limited information exists on the human pharmacokinetics of OH-PAHs. This study aimed to investigate the excretion half-life of 1-hydroxypyrene (1-PYR), the most
T Kuljukka et al.
Environmental health perspectives, 104 Suppl 3, 539-541 (1996-05-01)
The exposure of Estonian cokery workers to polynuclear aromatic hydrocarbons at an oil shale processing plant was assessed by occupational hygiene and biomonitoring measurements. To assess the external dose of exposure to polynuclear aromatic hydrocarbons, pyrene and benzo[a]pyrene concentrations were
Heiman F L Wertheim et al.
Environmental health : a global access science source, 11, 72-72 (2012-09-28)
Urban air pollution is an increasing health problem, particularly in Asia, where the combustion of fossil fuels has increased rapidly as a result of industrialization and socio-economic development. The adverse health impacts of urban air pollution are well established, but
P Strickland et al.
Toxicology letters, 108(2-3), 191-199 (1999-10-08)
Humans are exposed to polycyclic aromatic hydrocarbons (PAHs) from occupational, environmental, medicinal and dietary sources. PAH metabolites in human urine can be used as biomarkers of internal dose to assess recent exposure to PAHs. The most widely used urinary PAH
Thomas W Fuller et al.
Scientific reports, 8(1), 507-507 (2018-01-13)
Electronic cigarette (EC) use is gaining popularity as a substitute for conventional smoking due to the perception and evidence it represents a safer alternative. In contrast to the common perception amongst users that ECs represent no risk initial studies have
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