所有图片(1)

文件

361518

1-羟基芘

Name: 1-羟基芘
Brand: ALDRICH

98%

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别名:

1-Pyrenol

经验公式（希尔记法）:

C₁₆H₁₀O

CAS号:

5315-79-7

分子量:

218.25

MDL编号:

MFCD00044543

PubChem化学物质编号:

24862229

NACRES:

NA.22

质量水平

100

检测方案

98%

mp

179-182 °C (lit.)

SMILES字符串

Oc1ccc2ccc3cccc4ccc1c2c34

InChI

1S/C16H10O/c17-14-9-7-12-5-4-10-2-1-3-11-6-8-13(14)16(12)15(10)11/h1-9,17H

InChI key

BIJNHUAPTJVVNQ-UHFFFAOYSA-N

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一般描述

1-羟基芘作为尿液代谢产物，是多环芳烃 (PAH) 暴露的标志物。1-羟基芘是暴露于芘的重要生物标志物。

应用

1-羟基芘适用于以下研究：

探讨用简单的荧光法快速检测和定量测定暴露于沉积物相关芘的杂色沙蚕组织提取液中的 1-羟基芘。
探讨细胞色素 P450 1A1 (CYP1A1) 和 2E1 (CYP2E1) 以及谷胱甘肽 S-转移酶 mu (GSTM1) 和 θ (GSTT1) 的基因多态性对飞机维修工人尿 1-羟基芘和 2-萘酚水平的影响。
研究爱沙尼亚油页岩加工厂焦化厂工人的多环芳烃暴露情况。

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

dust mask type N95 (US), Eyeshields, Gloves

分析证书(COA)

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示例

T1503

货号

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MMYOMAG-74K-13

1000309185

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索取COA

Exposure to PAH compounds among cokery workers in the oil shale industry.

T Kuljukka et al.

Environmental health perspectives, 104 Suppl 3, 539-541 (1996-05-01)

The exposure of Estonian cokery workers to polynuclear aromatic hydrocarbons at an oil shale processing plant was assessed by occupational hygiene and biomonitoring measurements. To assess the external dose of exposure to polynuclear aromatic hydrocarbons, pyrene and benzo[a]pyrene concentrations were

Comparison of Bladder Carcinogens in the Urine of E-cigarette Users Versus Non E-cigarette Using Controls.

Thomas W Fuller et al.

Scientific reports, 8(1), 507-507 (2018-01-13)

Electronic cigarette (EC) use is gaining popularity as a substitute for conventional smoking due to the perception and evidence it represents a safer alternative. In contrast to the common perception amongst users that ECs represent no risk initial studies have

Mouth-level intake of benzo[a]pyrene from reduced nicotine cigarettes.

Yan S Ding et al.

International journal of environmental research and public health, 11(11), 11898-11914 (2014-11-21)

Cigarette smoke is a known source of exposure to carcinogenic polycyclic aromatic hydrocarbons (PAHs), especially benzo[a]pyrene (BaP). Exposure to BaP in cigarette smoke is influenced by how a person smokes and factors, such as tobacco blend. To determine whether sustained

Studying the effectiveness of activated carbon R95 respirators in reducing the inhalation of combustion by-products in Hanoi, Vietnam: a demonstration study.

Heiman F L Wertheim et al.

Environmental health : a global access science source, 11, 72-72 (2012-09-28)

Urban air pollution is an increasing health problem, particularly in Asia, where the combustion of fossil fuels has increased rapidly as a result of industrialization and socio-economic development. The adverse health impacts of urban air pollution are well established, but

Urinary 1-hydroxypyrene and other PAH metabolites as biomarkers of exposure to environmental PAH in air particulate matter.

P Strickland et al.

Toxicology letters, 108(2-3), 191-199 (1999-10-08)

Humans are exposed to polycyclic aromatic hydrocarbons (PAHs) from occupational, environmental, medicinal and dietary sources. PAH metabolites in human urine can be used as biomarkers of internal dose to assess recent exposure to PAHs. The most widely used urinary PAH

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