主要文件

查看所有文档

363057

6-O-甲基鸟嘌呤

Name: 6-<I>O</I>-甲基鸟嘌呤
Brand: ALDRICH

97%

别名:

2-氨基-6-甲氧基嘌呤, 6-甲氧基鸟嘌呤

登录查看组织和合同定价。

选择尺寸

变更视图

关于此项目

经验公式（希尔记法）:

C₆H₇N₅O

化学文摘社编号:

20535-83-5

分子量:

165.15

UNSPSC Code:

12352100

NACRES:

NA.22

PubChem Substance ID:

24862349

MDL number:

MFCD00133009

Beilstein/REAXYS Number:

645384

Assay:

97%

技术服务

需要帮助？我们经验丰富的科学家团队随时乐意为您服务。

让我们为您提供帮助

属性

Quality Level

200

assay

97%

mp

>300 °C (lit.)

SMILES string

COc1nc(N)nc2[nH]cnc12

InChI

1S/C6H7N5O/c1-12-5-3-4(9-2-8-3)10-6(7)11-5/h2H,1H3,(H3,7,8,9,10,11)

InChI key

BXJHWYVXLGLDMZ-UHFFFAOYSA-N

Gene Information

human ... CDK2(1017), MGMT(4255)

说明

General description

6-O-甲基鸟嘌呤是一种嘌呤衍生物，它的结合亲和力已通过使用等温滴定热法（ITC）利用枯草芽孢杆菌xpt-pbuX鸟嘌呤核糖开关（GR）进行了检查。6-O-甲基鸟嘌呤是在一系列纯化的tRNA制剂的烷基化过程中通过与致癌物N-甲基-N-亚硝基脲反应而形成的。

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

没有发现合适的版本？

如果您需要特殊版本，可通过批号或批次号查找具体证书。

搜索COA

已有该产品？

在文件库中查找您最近购买产品的文档。

访问文档库

[Induction of repair enzyme O6-methylguanine-DNA methyltransferase gene expression under the influence of cytokine EMAP II in human cells in vitro].

V V Lylo et al.

TSitologiia i genetika, 45(6), 53-60 (2012-02-15)

The aim of our study was to investigate the effect of recombinant human cytokine EMAP II (endothelial monocyte-activating polypeptide II) on the expression of MGMT gene, encoding repair enzyme O6-methylguanine-DNA methyltransferase (MGMT) in human cell cultures. The influence of EMAP

Temozolomide: mechanisms of action, repair and resistance.

Jihong Zhang et al.

Current molecular pharmacology, 5(1), 102-114 (2011-11-30)

Glioblastoma multiforme is the most common aggressive adult primary tumour of the central nervous system. Treatment includes surgery, radiotherapy and adjuvant temozolomide (TMZ) chemotherapy. TMZ is an alkylating agent prodrug, delivering a methyl group to purine bases of DNA (O6-guanine;

Chronic nicotine consumption does not influence 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone-induced lung tumorigenesis.

Sharon E Murphy et al.

Cancer prevention research (Philadelphia, Pa.), 4(11), 1752-1760 (2011-10-27)

Nicotine replacement therapy is often used to maintain smoking cessation. However, concerns exist about the safety of long-term nicotine replacement therapy use in ex-smokers and its concurrent use in smokers. In this study, we determined the effect of nicotine administration

查看所有相关文献

全球贸易项目编号

货号	GTIN
363057-500MG	04061833472989